2004年第66卷06期
共37篇1. Protein kinase C activation enhances morphine-induced rapid desensitization of mu-opioid receptors in mature rat locus ceruleus neurons. 1592-8页
作者:Christopher P,Bailey; Eamonn,Kelly; Graeme,Henderson
2. Long-term exposure to nicotine modulates the level and activity of acetylcholine receptors in white blood cells of smokers and model mice. 1712-8页
作者:Anne,Cormier; Yoav,Paas; Roland,Zini; Jean-Paul,Tillement; Gilbert,Lagrue; Jean-Pierre,Changeux; Régis,Grailhe
3. Single-cell imaging of intracellular Ca2+ and phospholipase C activity reveals that RGS 2, 3, and 4 differentially regulate signaling via the Galphaq/11-linked muscarinic M3 receptor. 1453-64页
作者:Stephen C,Tovey; Gary B,Willars
4. Regulation of cyclin-dependent kinase 5 and calcium/calmodulin-dependent protein kinase II by phosphatidylinositol-linked dopamine receptor in rat brain. 1500-7页
作者:Xuechu,Zhen; Satindra,Goswami; Syed Amir,Abdali; Mara,Gil; Kalindi,Bakshi; Eitan,Friedman
6. Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors. 1599-606页
作者:Tomoko,Kadowaki; Atsuyo,Baba; Naoko,Abe; Ryosuke,Takii; Munetaka,Hashimoto; Takayuki,Tsukuba; Shinji,Okazaki; Yoshimitsu,Suda; Tetsuji,Asao; Kenji,Yamamoto
7. Critical role of reactive oxygen species and mitochondrial membrane potential in Korean mistletoe lectin-induced apoptosis in human hepatocarcinoma cells. 1383-96页
作者:Won-Ho,Kim; Won Bong,Park; Bin,Gao; Myeong Ho,Jung
8. Impaired CREB-1 phosphorylation in antifolate-resistant cell lines with down-regulation of the reduced folate carrier gene. 1536-43页
作者:Lilah,Rothem; Michal,Stark; Yehuda G,Assaraf
9. Up-regulation of cyclooxygenase-2 expression is involved in R(+)-methanandamide-induced apoptotic death of human neuroglioma cells. 1643-51页
作者:Burkhard,Hinz; Robert,Ramer; Karin,Eichele; Ulrike,Weinzierl; Kay,Brune
10. Enhancement of cardiac L-type Ca2+ currents in transgenic mice with cardiac-specific overexpression of CYP2J2. 1607-16页
作者:Yong-Fu,Xiao; Qingen,Ke; John M,Seubert; J Alyce,Bradbury; Joan,Graves; Laura M,Degraff; John R,Falck; Kris,Krausz; Harry V,Gelboin; James P,Morgan; Darryl C,Zeldin
11. Selective modulation of ligand-gated P2X purinoceptor channels by acute hypoxia is mediated by reactive oxygen species. 1525-35页
作者:H S,Mason; S,Bourke; P J,Kemp
12. Designing transcription factor architectures for drug discovery. 1361-71页
作者:Pilar,Blancafort; David J,Segal; Carlos F,Barbas
13. Multiple actions of propofol on alphabetagamma and alphabetadelta GABAA receptors. 1517-24页
作者:Hua-Jun,Feng; Robert L,Macdonald
14. Specificity of the dihydroceramide desaturase inhibitor N-[(1R,2S)-2-hydroxy-1-hydroxymethyl-2-(2-tridecyl-1-cyclopropenyl)ethyl]octanamide (GT11) in primary cultured cerebellar neurons. 1671-8页
作者:Gemma,Triola; Gemma,Fabrias; Mihaela,Dragusin; Lars,Niederhausen; Roland,Broere; Amadeu,Llebaria; Gerhild,van Echten-Deckert
15. Preferential Interaction between the dopamine D2 receptor and Arrestin2 in neostriatal neurons. 1635-42页
作者:Tara A,Macey; Vsevolod V,Gurevich; Kim A,Neve
16. Alterations in receptor expression or agonist concentration change the pathways gastrin-releasing peptide receptor uses to regulate extracellular signal-regulated kinase. 1625-34页
作者:Pei-Wen,Chen; Glenn S,Kroog
17. Transcriptional regulation of the human mu-opioid receptor gene by interleukin-6. 1719-26页
作者:Christine,Börner; Jürgen,Kraus; Helmut,Schröder; Hermann,Ammer; Volker,Höllt
18. Mechanisms of agonist action at D2 dopamine receptors. 1573-9页
作者:David J,Roberts; Hong,Lin; Philip G,Strange
19. Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery. 1406-14页
作者:Chrystal M,Paulos; Joseph A,Reddy; Christopher P,Leamon; Mary Jo,Turk; Philip S,Low
20. The human sulfotransferase SULT1A1 gene is regulated in a synergistic manner by Sp1 and GA binding protein. 1690-701页
作者:Nadine,Hempel; Hongbing,Wang; Edward L,LeCluyse; Michael E,McManus; Masahiko,Negishi
21. Divergent effects of the purinoceptor antagonists suramin and pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) (PPNDS) on alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. 1738-47页
作者:Erika,Suzuki; Markus,Kessler; Kyle,Montgomery; Amy C,Arai
22. A novel computational approach for the prediction of networked transcription factors of aryl hydrocarbon-receptor-regulated genes. 1557-72页
作者:Alexander,Kel; Susanne,Reymann; Volker,Matys; Paul,Nettesheim; Edgar,Wingender; Jürgen,Borlak
23. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces suppressor of cytokine signaling 2 in murine B cells. 1662-70页
作者:Darrell R,Boverhof; Elaine,Tam; Allison S,Harney; Robert B,Crawford; Norbert E,Kaminski; Timothy R,Zacharewski
24. A retinoic acid receptor beta/gamma-selective prodrug (tazarotene) plus a retinoid X receptor ligand induces extracellular signal-regulated kinase activation, retinoblastoma hypophosphorylation, G0 arrest, and cell differentiation. 1727-37页
作者:Andrew,Yen; Robert,Fenning; Roshantha,Chandraratna; Patricia,Walker; Susi,Varvayanis
25. Doxorubicin inhibits DNMT1, resulting in conditional apoptosis. 1415-20页
作者:Tomoki,Yokochi; Keith D,Robertson
26. Certain 1,4-disubstituted aromatic piperidines and piperazines with extreme selectivity for the dopamine D4 receptor interact with a common receptor microdomain. 1491-9页
作者:Sandhya,Kortagere; Peter,Gmeiner; Harel,Weinstein; John A,Schetz
27. Oxidative stress and mitochondrial aldehyde dehydrogenase activity: a comparison of pentaerythritol tetranitrate with other organic nitrates. 1372-82页
作者:Andreas,Daiber; Matthias,Oelze; Meike,Coldewey; Markus,Bachschmid; Philip,Wenzel; Karsten,Sydow; Maria,Wendt; Andrei L,Kleschyov; Dirk,Stalleicken; Volker,Ullrich; Alexander,Mülsch; Thomas,Münzel
28. Using molecular tools to dissect the role of Galphas in sensitization of AC1. 1617-24页
作者:Timothy A,Vortherms; Chau H,Nguyen; Catherine H,Berlot; Val J,Watts
29. Tibolone is metabolized by the 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four human isozymes of the aldo-keto reductase 1C subfamily: inversion of stereospecificity with a delta5(10)-3-ketosteroid. 1702-11页
作者:Stephan,Steckelbroeck; Yi,Jin; Busola,Oyesanmi; Helenius J,Kloosterboer; Trevor M,Penning
30. Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes. 1679-89页
作者:Susan J,Smith; Lenora B,Cieslinski; Robert,Newton; Louise E,Donnelly; Peter S,Fenwick; Andrew G,Nicholson; Peter J,Barnes; Mary S,Barnette; Mark A,Giembycz
31. Evidence that mitogen-activated protein kinase phosphatase-1 induction by proteasome inhibitors plays an antiapoptotic role. 1478-90页
作者:George W,Small; Yue Y,Shi; Natalie A,Edmund; Sivagurunathan,Somasundaram; Dominic T,Moore; Robert Z,Orlowski
32. Analysis of ATP-binding cassette transporter expression in drug-selected cell lines by a microarray dedicated to multidrug resistance. 1397-405页
作者:Jean-Philippe,Annereau; Gergely,Szakács; Charles J,Tucker; Angela,Arciello; Carol,Cardarelli; Jennifer,Collins; Sherry,Grissom; Barry R,Zeeberg; William,Reinhold; John N,Weinstein; Yves,Pommier; Richard S,Paules; Michael M,Gottesman
34. Galphaz inhibits serum response factor-dependent transcription by inhibiting Rho signaling. 1508-16页
作者:Parmesh,Dutt; Aron B,Jaffe; Keith D,Merdek; Alan,Hall; Deniz,Toksoz
35. Signaling and ligand binding by recombinant neuromedin U receptors: evidence for dual coupling to Galphaq/11 and Galphai and an irreversible ligand-receptor interaction. 1544-56页
作者:Paul J,Brighton; Philip G,Szekeres; Alan,Wise; Gary B,Willars