2010年第6卷09期
共59篇1. Mice doubly-deficient in lysosomal hexosaminidase A and neuraminidase 4 show epileptic crises and rapid neuronal loss. e1001118页
作者:Volkan,Seyrantepe; Pablo,Lema; Aurore,Caqueret; Larbi,Dridi; Samar,Bel Hadj; Stephane,Carpentier; Francine,Boucher; Thierry,Levade; Lionel,Carmant; Roy A,Gravel; Edith,Hamel; Pascal,Vachon; Graziella,Di Cristo; Jacques L,Michaud; Carlos R,Morales; Alexey V,Pshezhetsky
2. The metabolic enzyme ManA reveals a link between cell wall integrity and chromosome morphology. e1001119页
作者:Maya,Elbaz; Sigal,Ben-Yehuda
3. Effect of correlated tRNA abundances on translation errors and evolution of codon usage bias. e1001128页
作者:Premal,Shah; Michael A,Gilchrist
4. The characterization of twenty sequenced human genomes. e1001111页
作者:Kimberly,Pelak; Kevin V,Shianna; Dongliang,Ge; Jessica M,Maia; Mingfu,Zhu; Jason P,Smith; Elizabeth T,Cirulli; Jacques,Fellay; Samuel P,Dickson; Curtis E,Gumbs; Erin L,Heinzen; Anna C,Need; Elizabeth K,Ruzzo; Abanish,Singh; C Ryan,Campbell; Linda K,Hong; Katharina A,Lornsen; Alexander M,McKenzie; Nara L M,Sobreira; Julie E,Hoover-Fong; Joshua D,Milner; Ruth,Ottman; Barton F,Haynes; James J,Goedert; David B,Goldstein
5. Proteomic changes resulting from gene copy number variations in cancer cells. e1001090页
作者:Tamar,Geiger; Juergen,Cox; Matthias,Mann
6. The potential for enhancing the power of genetic association studies in African Americans through the reuse of existing genotype data. e1001096页
作者:Gary K,Chen; Robert C,Millikan; Esther M,John; Christine B,Ambrosone; Leslie,Bernstein; Wei,Zheng; Jennifer J,Hu; Stephen J,Chanock; Regina G,Ziegler; Elisa V,Bandera; Brian E,Henderson; Christopher A,Haiman; Daniel O,Stram
7. Chromatin landscape dictates HSF binding to target DNA elements. e1001114页
作者:Michael J,Guertin; John T,Lis
8. An insect herbivore microbiome with high plant biomass-degrading capacity. e1001129页
作者:Garret,Suen; Jarrod J,Scott; Frank O,Aylward; Sandra M,Adams; Susannah G,Tringe; Adrián A,Pinto-Tomás; Clifton E,Foster; Markus,Pauly; Paul J,Weimer; Kerrie W,Barry; Lynne A,Goodwin; Pascal,Bouffard; Lewyn,Li; Jolene,Osterberger; Timothy T,Harkins; Steven C,Slater; Timothy J,Donohue; Cameron R,Currie
9. Orphan CpG islands identify numerous conserved promoters in the mammalian genome. e1001134页
作者:Robert S,Illingworth; Ulrike,Gruenewald-Schneider; Shaun,Webb; Alastair R W,Kerr; Keith D,James; Daniel J,Turner; Colin,Smith; David J,Harrison; Robert,Andrews; Adrian P,Bird
10. Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease. e1001087页
作者:Oyinkan,Sofola; Fiona,Kerr; Iain,Rogers; Richard,Killick; Hrvoje,Augustin; Carina,Gandy; Marcus J,Allen; John,Hardy; Simon,Lovestone; Linda,Partridge
11. A central regulatory system largely controls transcriptional activation and repression responses to phosphate starvation in Arabidopsis. e1001102页
作者:Regla,Bustos; Gabriel,Castrillo; Francisco,Linhares; María Isabel,Puga; Vicente,Rubio; Julian,Pérez-Pérez; Roberto,Solano; Antonio,Leyva; Javier,Paz-Ares
12. Widespread over-expression of the X chromosome in sterile F₁hybrid mice. e1001148页
作者:Jeffrey M,Good; Thomas,Giger; Matthew D,Dean; Michael W,Nachman
13. The APETALA-2-like transcription factor OsAP2-39 controls key interactions between abscisic acid and gibberellin in rice. e1001098页
作者:Mahmoud W,Yaish; Ashraf,El-Kereamy; Tong,Zhu; Perrin H,Beatty; Allen G,Good; Yong-Mei,Bi; Steven J,Rothstein
14. Comparative Genomic Hybridization (CGH) reveals a neo-X chromosome and biased gene movement in stalk-eyed flies (genus Teleopsis). e1001121页
作者:Richard H,Baker; Gerald S,Wilkinson
15. SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease. e1001101页
作者:Carlos,Cruchaga; John S K,Kauwe; Kevin,Mayo; Noah,Spiegel; Sarah,Bertelsen; Petra,Nowotny; Aarti R,Shah; Richard,Abraham; Paul,Hollingworth; Denise,Harold; Michael M,Owen; Julie,Williams; Simon,Lovestone; Elaine R,Peskind; Ge,Li; James B,Leverenz; Douglas,Galasko; Alzheimer's Disease Neuroimaging Initiative; John C,Morris; Anne M,Fagan; David M,Holtzman; Alison M,Goate
16. Germline variation controls the architecture of somatic alterations in tumors. e1001136页
作者:Amy M,Dworkin; Katie,Ridd; Dianne,Bautista; Dawn C,Allain; O Hans,Iwenofu; Ritu,Roy; Boris C,Bastian; Amanda Ewart,Toland
17. An immune response network associated with blood lipid levels. e1001113页
作者:Michael,Inouye; Kaisa,Silander; Eija,Hamalainen; Veikko,Salomaa; Kennet,Harald; Pekka,Jousilahti; Satu,Männistö; Johan G,Eriksson; Janna,Saarela; Samuli,Ripatti; Markus,Perola; Gert-Jan B,van Ommen; Marja-Riitta,Taskinen; Aarno,Palotie; Emmanouil T,Dermitzakis; Leena,Peltonen
18. Genetic deletion of the desmosomal component desmoplakin promotes tumor microinvasion in a mouse model of pancreatic neuroendocrine carcinogenesis. e1001120页
作者:Matthew G H,Chun; Douglas,Hanahan
19. Evidence of selection upon genomic GC-content in bacteria. e1001107页
作者:Falk,Hildebrand; Axel,Meyer; Adam,Eyre-Walker
20. Loss of maternal ATRX results in centromere instability and aneuploidy in the mammalian oocyte and pre-implantation embryo. e1001137页
作者:Claudia,Baumann; Maria M,Viveiros; Rabindranath,De La Fuente
21. Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function. e1001097页
作者:Soumya,Raychaudhuri; Joshua M,Korn; Steven A,McCarroll; International Schizophrenia Consortium; David,Altshuler; Pamela,Sklar; Shaun,Purcell; Mark J,Daly
22. The baker's yeast diploid genome is remarkably stable in vegetative growth and meiosis. e1001109页
作者:K T,Nishant; Wu,Wei; Eugenio,Mancera; Juan Lucas,Argueso; Andreas,Schlattl; Nicolas,Delhomme; Xin,Ma; Carlos D,Bustamante; Jan O,Korbel; Zhenglong,Gu; Lars M,Steinmetz; Eric,Alani
23. A negative regulatory loop between microRNA and Hox gene controls posterior identities in Caenorhabditis elegans. e1001089页
作者:Zhongying,Zhao; Thomas J,Boyle; Zongzhi,Liu; John I,Murray; William B,Wood; Robert H,Waterston
24. A single cis element maintains repression of the key developmental regulator Gata2. e1001103页
作者:Jonathan W,Snow; Jennifer J,Trowbridge; Tohru,Fujiwara; Nikla E,Emambokus; Jeffrey A,Grass; Stuart H,Orkin; Emery H,Bresnick
25. Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study. e1001094页
作者:Erin N,Smith; Wei,Chen; Mika,Kähönen; Johannes,Kettunen; Terho,Lehtimäki; Leena,Peltonen; Olli T,Raitakari; Rany M,Salem; Nicholas J,Schork; Marian,Shaw; Sathanur R,Srinivasan; Eric J,Topol; Jorma S,Viikari; Gerald S,Berenson; Sarah S,Murray
26. ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans. e1001125页
作者:Bargavi,Thyagarajan; Adam G,Blaszczak; Katherine J,Chandler; Jennifer L,Watts; W Evan,Johnson; Barbara J,Graves
27. Identification of early requirements for preplacodal ectoderm and sensory organ development. e1001133页
作者:Hye-Joo,Kwon; Neha,Bhat; Elly M,Sweet; Robert A,Cornell; Bruce B,Riley
28. FliO regulation of FliP in the formation of the Salmonella enterica flagellum. e1001143页
作者:Clive S,Barker; Irina V,Meshcheryakova; Alla S,Kostyukova; Fadel A,Samatey
29. Preferential re-replication of Drosophila heterochromatin in the absence of geminin. e1001112页
作者:Queying,Ding; David M,MacAlpine
30. Allelic selection of amplicons in glioblastoma revealed by combining somatic and germline analysis. e1001086页
作者:Thomas,LaFramboise; Ninad,Dewal; Katherine,Wilkins; Itsik,Pe'er; Matthew L,Freedman
31. DCAF26, an adaptor protein of Cul4-based E3, is essential for DNA methylation in Neurospora crassa. e1001132页
作者:Hui,Xu; Jiyong,Wang; Qiwen,Hu; Yun,Quan; Huijie,Chen; Yingqiong,Cao; Chunbo,Li; Ying,Wang; Qun,He
32. Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis. e1001141页
作者:Qi,Zheng; Paul,Ryvkin; Fan,Li; Isabelle,Dragomir; Otto,Valladares; Jamie,Yang; Kajia,Cao; Li-San,Wang; Brian D,Gregory
33. dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cells. e1001140页
作者:Marcello,Ziosi; Luis Alberto,Baena-López; Daniela,Grifoni; Francesca,Froldi; Andrea,Pession; Flavio,Garoia; Vincenzo,Trotta; Paola,Bellosta; Sandro,Cavicchi; Annalisa,Pession
34. Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data. e1001116页
作者:Abigail,Bigham; Marc,Bauchet; Dalila,Pinto; Xianyun,Mao; Joshua M,Akey; Rui,Mei; Stephen W,Scherer; Colleen G,Julian; Megan J,Wilson; David,López Herráez; Tom,Brutsaert; Esteban J,Parra; Lorna G,Moore; Mark D,Shriver
35. Cdc20 is critical for meiosis I and fertility of female mice. e1001147页
作者:Fang,Jin; Masakazu,Hamada; Liviu,Malureanu; Karthik B,Jeganathan; Wei,Zhou; Dean E,Morbeck; Jan M,van Deursen
36. Diversity of eukaryotic DNA replication origins revealed by genome-wide analysis of chromatin structure. e1001092页
作者:Nicolas M,Berbenetz; Corey,Nislow; Grant W,Brown
37. Optimal strategy for competence differentiation in bacteria. e1001108页
作者:C Scott,Wylie; Aaron D,Trout; David A,Kessler; Herbert,Levine
38. The SR protein B52/SRp55 is required for DNA topoisomerase I recruitment to chromatin, mRNA release and transcription shutdown. e1001124页
作者:François,Juge; Céline,Fernando; Weronika,Fic; Jamal,Tazi
39. Network analysis identifies ELF3 as a QTL for the shade avoidance response in Arabidopsis. e1001100页
作者:José M,Jiménez-Gómez; Andreah D,Wallace; Julin N,Maloof
40. Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: the cardiovascular risk in young Finns study. e1001146页
作者:Sebastian,Okser; Terho,Lehtimäki; Laura L,Elo; Nina,Mononen; Nina,Peltonen; Mika,Kähönen; Markus,Juonala; Yue-Mei,Fan; Jussi A,Hernesniemi; Tomi,Laitinen; Leo-Pekka,Lyytikäinen; Riikka,Rontu; Carita,Eklund; Nina,Hutri-Kähönen; Leena,Taittonen; Mikko,Hurme; Jorma S A,Viikari; Olli T,Raitakari; Tero,Aittokallio
41. Analysis of the Basidiomycete Coprinopsis cinerea reveals conservation of the core meiotic expression program over half a billion years of evolution. e1001135页
作者:Claire,Burns; Jason E,Stajich; Andreas,Rechtsteiner; Lorna,Casselton; Sean E,Hanlon; Sarah K,Wilke; Oleksandr P,Savytskyy; Allen C,Gathman; Walt W,Lilly; Jason D,Lieb; Miriam E,Zolan; Patricia J,Pukkila
42. Synthesizing and salvaging NAD: lessons learned from Chlamydomonas reinhardtii. e1001105页
作者:Huawen,Lin; Alan L,Kwan; Susan K,Dutcher
43. The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny. e1001091页
作者:Andreas,Rechtsteiner; Sevinc,Ercan; Teruaki,Takasaki; Taryn M,Phippen; Thea A,Egelhofer; Wenchao,Wang; Hiroshi,Kimura; Jason D,Lieb; Susan,Strome
44. Gene-environment interactions at nucleotide resolution. e1001144页
作者:Justin,Gerke; Kim,Lorenz; Shelina,Ramnarine; Barak,Cohen
45. Long- and short-term selective forces on malaria parasite genomes. e1001099页
作者:Sanne,Nygaard; Alexander,Braunstein; Gareth,Malsen; Stijn,Van Dongen; Paul P,Gardner; Anders,Krogh; Thomas D,Otto; Arnab,Pain; Matthew,Berriman; Jon,McAuliffe; Emmanouil T,Dermitzakis; Daniel C,Jeffares
46. Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA. e1001093页
作者:Julia Ling-Yu,Chen; Daniel,Merl; Christopher W,Peterson; Jianli,Wu; Patrick Yantyng,Liu; Hanwei,Yin; Deborah M,Muoio; Don E,Ayer; Mike,West; Jen-Tsan,Chi
47. DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo. e1001106页
作者:Bethany L,Wienholz; Michael S,Kareta; Amir H,Moarefi; Catherine A,Gordon; Paul A,Ginno; Frédéric,Chédin
48. Response to mechanical stress is mediated by the TRPA channel painless in the Drosophila heart. e1001088页
作者:Sébastien,Sénatore; Vatrapu,Rami Reddy; Michel,Sémériva; Laurent,Perrin; Nathalie,Lalevée
49. Evidence that mutation is universally biased towards AT in bacteria. e1001115页
作者:Ruth,Hershberg; Dmitri A,Petrov
50. Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress. e1001110页
作者:Chen-Hua,Chuang; Marsha D,Wallace; Christian,Abratte; Teresa,Southard; John C,Schimenti
51. Genetic architecture of complex traits and accuracy of genomic prediction: coat colour, milk-fat percentage, and type in Holstein cattle as contrasting model traits. e1001139页
作者:Ben J,Hayes; Jennie,Pryce; Amanda J,Chamberlain; Phil J,Bowman; Mike E,Goddard
52. Analysis of population structure: a unifying framework and novel methods based on sparse factor analysis. e1001117页
作者:Barbara E,Engelhardt; Matthew,Stephens
53. Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast. e1001138页
作者:Santiago,Cavero; Oliver,Limbo; Paul,Russell
54. Mutational patterns cannot explain genome composition: Are there any neutral sites in the genomes of bacteria? e1001104页
作者:Eduardo P C,Rocha; Edward J,Feil
56. Perturbation analysis of heterochromatin-mediated gene silencing and somatic inheritance. e1001095页
作者:Jonathan I,Schneiderman; Sara,Goldstein; Kami,Ahmad
57. Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities. e1001130页
作者:Adam C,Naj; Gary W,Beecham; Eden R,Martin; Paul J,Gallins; Eric H,Powell; Ioanna,Konidari; Patrice L,Whitehead; Guiqing,Cai; Vahram,Haroutunian; William K,Scott; Jeffery M,Vance; Michael A,Slifer; Harry E,Gwirtsman; John R,Gilbert; Jonathan L,Haines; Joseph D,Buxbaum; Margaret A,Pericak-Vance
58. The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions. e1001145页
作者:Michal,Letek; Patricia,González; Iain,Macarthur; Héctor,Rodríguez; Tom C,Freeman; Ana,Valero-Rello; Mónica,Blanco; Tom,Buckley; Inna,Cherevach; Ruth,Fahey; Alexia,Hapeshi; Jolyon,Holdstock; Desmond,Leadon; Jesús,Navas; Alain,Ocampo; Michael A,Quail; Mandy,Sanders; Mariela M,Scortti; John F,Prescott; Ursula,Fogarty; Wim G,Meijer; Julian,Parkhill; Stephen D,Bentley; José A,Vázquez-Boland
59. Commercially available outbred mice for genome-wide association studies. e1001085页
作者:Binnaz,Yalcin; Jérôme,Nicod; Amarjit,Bhomra; Stuart,Davidson; James,Cleak; Laurent,Farinelli; Magne,Østerås; Adam,Whitley; Wei,Yuan; Xiangchao,Gan; Martin,Goodson; Paul,Klenerman; Ansu,Satpathy; Diane,Mathis; Christophe,Benoist; David J,Adams; Richard,Mott; Jonathan,Flint