2012年第8卷05期
共58篇1. EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice. e1002723页
作者:Anne-Pierre,Morel; George W,Hinkal; Clémence,Thomas; Frédérique,Fauvet; Stéphanie,Courtois-Cox; Anne,Wierinckx; Mojgan,Devouassoux-Shisheboran; Isabelle,Treilleux; Agnès,Tissier; Baptiste,Gras; Julie,Pourchet; Isabelle,Puisieux; Gareth J,Browne; Douglas B,Spicer; Joël,Lachuer; Stéphane,Ansieau; Alain,Puisieux
2. New insight into the history of domesticated apple: secondary contribution of the European wild apple to the genome of cultivated varieties. e1002703页
作者:Amandine,Cornille; Pierre,Gladieux; Marinus J M,Smulders; Isabel,Roldán-Ruiz; François,Laurens; Bruno,Le Cam; Anush,Nersesyan; Joanne,Clavel; Marina,Olonova; Laurence,Feugey; Ivan,Gabrielyan; Xiu-Guo,Zhang; Maud I,Tenaillon; Tatiana,Giraud
3. Principles of carbon catabolite repression in the rice blast fungus: Tps1, Nmr1-3, and a MATE-family pump regulate glucose metabolism during infection. e1002673页
作者:Jessie,Fernandez; Janet D,Wright; David,Hartline; Cristian F,Quispe; Nandakumar,Madayiputhiya; Richard A,Wilson
4. TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans. e1002722页
作者:Mandy,Hannemann; Nikhil,Sasidharan; Jan,Hegermann; Lena M,Kutscher; Sabine,Koenig; Stefan,Eimer
5. Repeated, selection-driven genome reduction of accessory genes in experimental populations. e1002651页
作者:Ming-Chun,Lee; Christopher J,Marx
6. Target gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressors. e1002728页
作者:Julia,Heisig; David,Weber; Eva,Englberger; Anja,Winkler; Susanne,Kneitz; Wing-Kin,Sung; Elmar,Wolf; Martin,Eilers; Chia-Lin,Wei; Manfred,Gessler
7. Acquisition order of Ras and p53 gene alterations defines distinct adrenocortical tumor phenotypes. e1002700页
作者:Maryline,Herbet; Aude,Salomon; Jean-Jacques,Feige; Michaël,Thomas
8. Hypersensitive to red and blue 1 and its modification by protein phosphatase 7 are implicated in the control of Arabidopsis stomatal aperture. e1002674页
作者:Xiaodong,Sun; Xiaojun,Kang; Min,Ni
9. YY1 regulates melanocyte development and function by cooperating with MITF. e1002688页
作者:Juying,Li; Jun S,Song; Robert J A,Bell; Thanh-Nga T,Tran; Rizwan,Haq; Huifei,Liu; Kevin T,Love; Robert,Langer; Daniel G,Anderson; Lionel,Larue; David E,Fisher
10. Drosophila activated Cdc42 kinase has an anti-apoptotic function. e1002725页
作者:Jessica A,Schoenherr; J Michelle,Drennan; Juan S,Martinez; Madhusudana Rao,Chikka; Mark C,Hall; Henry C,Chang; James C,Clemens
11. Fitness landscape transformation through a single amino acid change in the rho terminator. e1002744页
作者:Peter L,Freddolino; Hani,Goodarzi; Saeed,Tavazoie
12. Meiotic chromosome pairing is promoted by telomere-led chromosome movements independent of bouquet formation. e1002730页
作者:Chih-Ying,Lee; Michael N,Conrad; Michael E,Dresser
13. Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases. e1002746页
作者:Rui,Li; Felix F,Brockschmidt; Amy K,Kiefer; Hreinn,Stefansson; Dale R,Nyholt; Kijoung,Song; Sita H,Vermeulen; Stavroula,Kanoni; Daniel,Glass; Sarah E,Medland; Maria,Dimitriou; Dawn,Waterworth; Joyce Y,Tung; Frank,Geller; Stefanie,Heilmann; Axel M,Hillmer; Veronique,Bataille; Sibylle,Eigelshoven; Sandra,Hanneken; Susanne,Moebus; Christine,Herold; Martin,den Heijer; Grant W,Montgomery; Panos,Deloukas; Nicholas,Eriksson; Andrew C,Heath; Tim,Becker; Patrick,Sulem; Massimo,Mangino; Peter,Vollenweider; Tim D,Spector; George,Dedoussis; Nicholas G,Martin; Lambertus A,Kiemeney; Vincent,Mooser; Kari,Stefansson; David A,Hinds; Markus M,Nöthen; J Brent,Richards
14. Functional centromeres determine the activation time of pericentric origins of DNA replication in Saccharomyces cerevisiae. e1002677页
作者:Thomas J,Pohl; Bonita J,Brewer; M K,Raghuraman
15. Extent, causes, and consequences of small RNA expression variation in human adipose tissue. e1002704页
作者:Leopold,Parts; Åsa K,Hedman; Sarah,Keildson; Andrew J,Knights; Cei,Abreu-Goodger; Martijn,van de Bunt; José Afonso,Guerra-Assunção; Nenad,Bartonicek; Stijn,van Dongen; Reedik,Mägi; James,Nisbet; Amy,Barrett; Mattias,Rantalainen; Alexandra C,Nica; Michael A,Quail; Kerrin S,Small; Daniel,Glass; Anton J,Enright; John,Winn; MuTHER Consortium; Panos,Deloukas; Emmanouil T,Dermitzakis; Mark I,McCarthy; Timothy D,Spector; Richard,Durbin; Cecilia M,Lindgren
16. Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo. e1002690页
作者:Chaitali,Misra; Nita,Sachan; Caryn Rothrock,McNally; Sara N,Koenig; Haley A,Nichols; Anuradha,Guggilam; Pamela A,Lucchesi; William T,Pu; Deepak,Srivastava; Vidu,Garg
17. ELK1 uses different DNA binding modes to regulate functionally distinct classes of target genes. e1002694页
作者:Zaneta,Odrowaz; Andrew D,Sharrocks
18. Regulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic states. e1002727页
作者:Stephanie,Kueng; Monika,Tsai-Pflugfelder; Mariano,Oppikofer; Helder C,Ferreira; Emma,Roberts; Chinyen,Tsai; Tim-Christoph,Roloff; Ragna,Sack; Susan M,Gasser
19. Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome. e1002692页
作者:Jian,Li; R Alan,Harris; Sau Wai,Cheung; Cristian,Coarfa; Mira,Jeong; Margaret A,Goodell; Lisa D,White; Ankita,Patel; Sung-Hae,Kang; Chad,Shaw; A Craig,Chinault; Tomasz,Gambin; Anna,Gambin; James R,Lupski; Aleksandar,Milosavljevic
20. MicroRNA-277 modulates the neurodegeneration caused by Fragile X premutation rCGG repeats. e1002681页
作者:Huiping,Tan; Mickael,Poidevin; He,Li; Dahua,Chen; Peng,Jin
21. Separation of DNA replication from the assembly of break-competent meiotic chromosomes. e1002643页
作者:Hannah G,Blitzblau; Clara S,Chan; Andreas,Hochwagen; Stephen P,Bell
22. Histone h1 depletion impairs embryonic stem cell differentiation. e1002691页
作者:Yunzhe,Zhang; Marissa,Cooke; Shiraj,Panjwani; Kaixiang,Cao; Beth,Krauth; Po-Yi,Ho; Magdalena,Medrzycki; Dawit T,Berhe; Chenyi,Pan; Todd C,McDevitt; Yuhong,Fan
23. Karyotypic determinants of chromosome instability in aneuploid budding yeast. e1002719页
作者:Jin,Zhu; Norman,Pavelka; William D,Bradford; Giulia,Rancati; Rong,Li
24. The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model. e1002724页
作者:Matthieu,Raveau; Jacques M,Lignon; Valérie,Nalesso; Arnaud,Duchon; Yoram,Groner; Andrew J,Sharp; Doulaye,Dembele; Véronique,Brault; Yann,Hérault
25. Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis. e1002735页
作者:Scott F,Winter; Luanne,Lukes; Renard C,Walker; Danny R,Welch; Kent W,Hunter
26. Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. e1002711页
作者:Giorgio Giacomo,Galli; Kristian,Honnens de Lichtenberg; Matteo,Carrara; Wolfgang,Hans; Manuela,Wuelling; Bettina,Mentz; Hinke Arnolda,Multhaupt; Cathrine Kolster,Fog; Klaus Thorleif,Jensen; Juri,Rappsilber; Andrea,Vortkamp; Les,Coulton; Helmut,Fuchs; Valérie,Gailus-Durner; Martin,Hrabě de Angelis; Raffaele Adolfo,Calogero; John Robert,Couchman; Anders Henrik,Lund
27. The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity. e1002647页
作者:Julien,Vandamme; Gaëlle,Lettier; Simone,Sidoli; Elia,Di Schiavi; Ole,Nørregaard Jensen; Anna Elisabetta,Salcini
28. Neurospora COP9 signalosome integrity plays major roles for hyphal growth, conidial development, and circadian function. e1002712页
作者:Zhipeng,Zhou; Ying,Wang; Gaihong,Cai; Qun,He
29. Slowing replication in preparation for reduction. e1002715页
作者:Katherine S,Lawrence; Joanne,Engebrecht
31. Downregulation of chloroplast RPS1 negatively modulates nuclear heat-responsive expression of HsfA2 and its target genes in Arabidopsis. e1002669页
作者:Hai-Dong,Yu; Xiao-Fei,Yang; Si-Ting,Chen; Yu-Ting,Wang; Ji-Kai,Li; Qi,Shen; Xun-Liang,Liu; Fang-Qing,Guo
32. Integrin α PAT-2/CDC-42 signaling is required for muscle-mediated clearance of apoptotic cells in Caenorhabditis elegans. e1002663页
作者:Hsiao-Han,Hsieh; Tsung-Yuan,Hsu; Hang-Shiang,Jiang; Yi-Chun,Wu
33. LINT, a novel dL(3)mbt-containing complex, represses malignant brain tumour signature genes. e1002676页
作者:Karin,Meier; Eve-Lyne,Mathieu; Florian,Finkernagel; L Maximilian,Reuter; Maren,Scharfe; Gunther,Doehlemann; Michael,Jarek; Alexander,Brehm
35. Using whole-genome sequence data to predict quantitative trait phenotypes in Drosophila melanogaster. e1002685页
作者:Ulrike,Ober; Julien F,Ayroles; Eric A,Stone; Stephen,Richards; Dianhui,Zhu; Richard A,Gibbs; Christian,Stricker; Daniel,Gianola; Martin,Schlather; Trudy F C,Mackay; Henner,Simianer
36. Deletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- mice. e1002726页
作者:Quan,Yuan; Tadatoshi,Sato; Michael,Densmore; Hiroaki,Saito; Christiane,Schüler; Reinhold G,Erben; Beate,Lanske
37. IDN2 and its paralogs form a complex required for RNA-directed DNA methylation. e1002693页
作者:Cui-Jun,Zhang; Yong-Qiang,Ning; Su-Wei,Zhang; Qing,Chen; Chang-Rong,Shao; Yan-Wu,Guo; Jin-Xing,Zhou; Lin,Li; She,Chen; Xin-Jian,He
38. UDP-galactose 4'-epimerase activities toward UDP-Gal and UDP-GalNAc play different roles in the development of Drosophila melanogaster. e1002721页
作者:Jennifer M I,Daenzer; Rebecca D,Sanders; Darwin,Hang; Judith L,Fridovich-Keil
39. DNA demethylation and USF regulate the meiosis-specific expression of the mouse Miwi. e1002716页
作者:Yu,Hou; Jia,Yuan; Xiang,Zhou; Xiazhou,Fu; Hanhua,Cheng; Rongjia,Zhou
40. The number of x chromosomes causes sex differences in adiposity in mice. e1002709页
作者:Xuqi,Chen; Rebecca,McClusky; Jenny,Chen; Simon W,Beaven; Peter,Tontonoz; Arthur P,Arnold; Karen,Reue
41. Loss of Gnas imprinting differentially affects REM/NREM sleep and cognition in mice. e1002706页
作者:Glenda,Lassi; Simon T,Ball; Silvia,Maggi; Giovanni,Colonna; Thierry,Nieus; Cheryl,Cero; Alessandro,Bartolomucci; Jo,Peters; Valter,Tucci
42. Dynamic deposition of histone variant H3.3 accompanies developmental remodeling of the Arabidopsis transcriptome. e1002658页
作者:Heike,Wollmann; Sarah,Holec; Keith,Alden; Neil D,Clarke; Pierre-Étienne,Jacques; Frédéric,Berger
43. Genome-wide analysis of GLD-1-mediated mRNA regulation suggests a role in mRNA storage. e1002742页
作者:Claudia,Scheckel; Dimos,Gaidatzis; Jane E,Wright; Rafal,Ciosk
44. A duplication CNV that conveys traits reciprocal to metabolic syndrome and protects against diet-induced obesity in mice and men. e1002713页
作者:Melanie,Lacaria; Pradip,Saha; Lorraine,Potocki; Weimin,Bi; Jiong,Yan; Santhosh,Girirajan; Brooke,Burns; Sarah,Elsea; Katherina,Walz; Lawrence,Chan; James R,Lupski; Wenli,Gu
45. Collapse of telomere homeostasis in hematopoietic cells caused by heterozygous mutations in telomerase genes. e1002696页
作者:Geraldine,Aubert; Gabriela M,Baerlocher; Irma,Vulto; Steven S,Poon; Peter M,Lansdorp
46. Histone H3 localizes to the centromeric DNA in budding yeast. e1002739页
作者:Berit,Lochmann; Dmitri,Ivanov
47. Bmps and id2a act upstream of Twist1 to restrict ectomesenchyme potential of the cranial neural crest. e1002710页
48. abd-A regulation by the iab-8 noncoding RNA. e1002720页
作者:Maheshwar,Gummalla; Robert K,Maeda; Javier J,Castro Alvarez; Henrik,Gyurkovics; Swetha,Singari; Kevin A,Edwards; François,Karch; Welcome,Bender
49. Identification of genes that promote or antagonize somatic homolog pairing using a high-throughput FISH-based screen. e1002667页
作者:Eric F,Joyce; Benjamin R,Williams; Tiao,Xie; C-Ting,Wu
50. Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice. e1002708页
作者:Xiaofang,Wang; Suzhen,Wang; Changcheng,Li; Tian,Gao; Ying,Liu; Afsaneh,Rangiani; Yao,Sun; Jianjun,Hao; Anne,George; Yongbo,Lu; Jay,Groppe; Baozhi,Yuan; Jian Q,Feng; Chunlin,Qin
51. Re-patterning sleep architecture in Drosophila through gustatory perception and nutritional quality. e1002668页
作者:Nancy J,Linford; Tammy P,Chan; Scott D,Pletcher
53. An essential role for katanin p80 and microtubule severing in male gamete production. e1002698页
作者:Liza,O'Donnell; Danielle,Rhodes; Stephanie J,Smith; D Jo,Merriner; Brett J,Clark; Claire,Borg; Belinda,Whittle; Anne E,O'Connor; Lee B,Smith; Francis J,McNally; David M,de Kretser; Chris C,Goodnow; Chris J,Ormandy; Duangporn,Jamsai; Moira K,O'Bryan
54. Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis. e1002650页
作者:Phuoc T,Tran; Emelyn H,Shroff; Timothy F,Burns; Saravanan,Thiyagarajan; Sandhya T,Das; Tahera,Zabuawala; Joy,Chen; Yoon-Jae,Cho; Richard,Luong; Pablo,Tamayo; Tarek,Salih; Khaled,Aziz; Stacey J,Adam; Silvestre,Vicent; Carsten H,Nielsen; Nadia,Withofs; Alejandro,Sweet-Cordero; Sanjiv S,Gambhir; Charles M,Rudin; Dean W,Felsher
55. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. e1002695页
作者:Caroline S,Fox; Yongmei,Liu; Charles C,White; Mary,Feitosa; Albert V,Smith; Nancy,Heard-Costa; Kurt,Lohman; GIANT Consortium; MAGIC Consortium; GLGC Consortium; Andrew D,Johnson; Meredith C,Foster; Danielle M,Greenawalt; Paula,Griffin; Jinghong,Ding; Anne B,Newman; Fran,Tylavsky; Iva,Miljkovic; Stephen B,Kritchevsky; Lenore,Launer; Melissa,Garcia; Gudny,Eiriksdottir; J Jeffrey,Carr; Vilmunder,Gudnason; Tamara B,Harris; L Adrienne,Cupples; Ingrid B,Borecki
56. Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing. e1002717页
作者:Madapura M,Pradeepa; Heidi G,Sutherland; Jernej,Ule; Graeme R,Grimes; Wendy A,Bickmore
57. Common genetic determinants of intraocular pressure and primary open-angle glaucoma. e1002611页
作者:Leonieke M E,van Koolwijk; Wishal D,Ramdas; M Kamran,Ikram; Nomdo M,Jansonius; Francesca,Pasutto; Pirro G,Hysi; Stuart,Macgregor; Sarah F,Janssen; Alex W,Hewitt; Ananth C,Viswanathan; Jacoline B,ten Brink; S Mohsen,Hosseini; Najaf,Amin; Dominiek D G,Despriet; Jacqueline J M,Willemse-Assink; Rogier,Kramer; Fernando,Rivadeneira; Maksim,Struchalin; Yurii S,Aulchenko; Nicole,Weisschuh; Matthias,Zenkel; Christian Y,Mardin; Eugen,Gramer; Ulrich,Welge-Lüssen; Grant W,Montgomery; Francis,Carbonaro; Terri L,Young; DCCT/EDIC Research Group; Céline,Bellenguez; Peter,McGuffin; Paul J,Foster; Fotis,Topouzis; Paul,Mitchell; Jie Jin,Wang; Tien Y,Wong; Monika A,Czudowska; Albert,Hofman; Andre G,Uitterlinden; Roger C W,Wolfs; Paulus T V M,de Jong; Ben A,Oostra; Andrew D,Paterson; Wellcome Trust Case Control Consortium 2; David A,Mackey; Arthur A B,Bergen; André,Reis; Christopher J,Hammond; Johannes R,Vingerling; Hans G,Lemij; Caroline C W,Klaver; Cornelia M,van Duijn
58. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. e1002741页
作者:John R B,Perry; Benjamin F,Voight; Loïc,Yengo; Najaf,Amin; Josée,Dupuis; Martha,Ganser; Harald,Grallert; Pau,Navarro; Man,Li; Lu,Qi; Valgerdur,Steinthorsdottir; Robert A,Scott; Peter,Almgren; Dan E,Arking; Yurii,Aulchenko; Beverley,Balkau; Rafn,Benediktsson; Richard N,Bergman; Eric,Boerwinkle; Lori,Bonnycastle; Noël P,Burtt; Harry,Campbell; Guillaume,Charpentier; Francis S,Collins; Christian,Gieger; Todd,Green; Samy,Hadjadj; Andrew T,Hattersley; Christian,Herder; Albert,Hofman; Andrew D,Johnson; Anna,Kottgen; Peter,Kraft; Yann,Labrune; Claudia,Langenberg; Alisa K,Manning; Karen L,Mohlke; Andrew P,Morris; Ben,Oostra; James,Pankow; Ann-Kristin,Petersen; Peter P,Pramstaller; Inga,Prokopenko; Wolfgang,Rathmann; William,Rayner; Michael,Roden; Igor,Rudan; Denis,Rybin; Laura J,Scott; Gunnar,Sigurdsson; Rob,Sladek; Gudmar,Thorleifsson; Unnur,Thorsteinsdottir; Jaakko,Tuomilehto; Andre G,Uitterlinden; Sidonie,Vivequin; Michael N,Weedon; Alan F,Wright; MAGIC; DIAGRAM Consortium; GIANT Consortium; Frank B,Hu; Thomas,Illig; Linda,Kao; James B,Meigs; James F,Wilson; Kari,Stefansson; Cornelia,van Duijn; David,Altschuler; Andrew D,Morris; Michael,Boehnke; Mark I,McCarthy; Philippe,Froguel; Colin N A,Palmer; Nicholas J,Wareham; Leif,Groop; Timothy M,Frayling; Stéphane,Cauchi