2021年第17卷04期
共61篇1. A structural signature motif enlightens the origin and diversification of nuclear receptors. e1009492页
作者:Brice,Beinsteiner; Gabriel V,Markov; Stéphane,Erb; Yassmine,Chebaro; Alastair G,McEwen; Sarah,Cianférani; Vincent,Laudet; Dino,Moras; Isabelle M L,Billas
2. Cell volume homeostatically controls the rDNA repeat copy number and rRNA synthesis rate in yeast. e1009520页
作者:José E,Pérez-Ortín; Adriana,Mena; Marina,Barba-Aliaga; Abhyudai,Singh; Sebastián,Chávez; José,García-Martínez
3. Extracellular spreading of Wingless is required for Drosophila oogenesis. e1009469页
作者:Xiaoxi,Wang; Kimberly S,LaFever; Indrayani,Waghmare; Andrea,Page-McCaw
4. Optogenetic delivery of trophic signals in a genetic model of Parkinson's disease. e1009479页
作者:Alvaro,Ingles-Prieto; Nikolas,Furthmann; Samuel H,Crossman; Alexandra-Madelaine,Tichy; Nina,Hoyer; Meike,Petersen; Vanessa,Zheden; Julia,Biebl; Eva,Reichhart; Attila,Gyoergy; Daria E,Siekhaus; Peter,Soba; Konstanze F,Winklhofer; Harald,Janovjak
5. A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment. e1009484页
作者:Thomas K,Pak; Calvin S,Carter; Qihong,Zhang; Sunny C,Huang; Charles,Searby; Ying,Hsu; Rebecca J,Taugher; Tim,Vogel; Christopher C,Cychosz; Rachel,Genova; Nina N,Moreira; Hanna,Stevens; John A,Wemmie; Andrew A,Pieper; Kai,Wang; Val C,Sheffield
6. Mitogen-activated protein kinase 6 negatively regulates secondary wall biosynthesis by modulating MYB46 protein stability in Arabidopsis thaliana. e1009510页
作者:Jong Hee,Im; Jae-Heung,Ko; Won-Chan,Kim; Brent,Crain; Daniel,Keathley; Kyung-Hwan,Han
7. Opposing roles for Egalitarian and Staufen in transport, anchoring and localization of oskar mRNA in the Drosophila oocyte. e1009500页
作者:Sabine,Mohr; Andrew,Kenny; Simon T Y,Lam; Miles B,Morgan; Craig A,Smibert; Howard D,Lipshitz; Paul M,Macdonald
8. The genomics of rapid climatic adaptation and parallel evolution in North American house mice. e1009495页
作者:Kathleen G,Ferris; Andreas S,Chavez; Taichi A,Suzuki; Elizabeth J,Beckman; Megan,Phifer-Rixey; Ke,Bi; Michael W,Nachman
9. Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior. e1009240页
作者:Colleen M,Palmateer; Shawn C,Moseley; Surjyendu,Ray; Savannah G,Brovero; Michelle N,Arbeitman
10. Genetic analysis of the septal peptidoglycan synthase FtsWI complex supports a conserved activation mechanism for SEDS-bPBP complexes. e1009366页
作者:Ying,Li; Han,Gong; Rui,Zhan; Shushan,Ouyang; Kyung-Tae,Park; Joe,Lutkenhaus; Shishen,Du
11. Aurora kinase A is essential for meiosis in mouse oocytes. e1009327页
作者:Cecilia S,Blengini; Patricia,Ibrahimian; Michaela,Vaskovicova; David,Drutovic; Petr,Solc; Karen,Schindler
12. Sex-stratified genome-wide association study of multisite chronic pain in UK Biobank. e1009428页
作者:Keira J A,Johnston; Joey,Ward; Pradipta R,Ray; Mark J,Adams; Andrew M,McIntosh; Blair H,Smith; Rona J,Strawbridge; Theodore J,Price; Daniel J,Smith; Barbara I,Nicholl; Mark E S,Bailey
13. PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer's disease. e1009406页
作者:Alex G,Nackenoff; Timothy J,Hohman; Sarah M,Neuner; Carolyn S,Akers; Nicole C,Weitzel; Alena,Shostak; Shawn M,Ferguson; Bret,Mobley; David A,Bennett; Julie A,Schneider; Angela L,Jefferson; Catherine C,Kaczorowski; Matthew S,Schrag
14. MRLocus: Identifying causal genes mediating a trait through Bayesian estimation of allelic heterogeneity. e1009455页
作者:Anqi,Zhu; Nana,Matoba; Emma P,Wilson; Amanda L,Tapia; Yun,Li; Joseph G,Ibrahim; Jason L,Stein; Michael I,Love
15. Multiplexed assays reveal effects of missense variants in MSH2 and cancer predisposition. e1009496页
作者:Sofie V,Nielsen; Rasmus,Hartmann-Petersen; Amelie,Stein; Kresten,Lindorff-Larsen
16. Selfish chromosomal drive shapes recent centromeric histone evolution in monkeyflowers. e1009418页
作者:Findley R,Finseth; Thomas C,Nelson; Lila,Fishman
17. DNA methylation-mediated modulation of rapid desiccation tolerance acquisition and dehydration stress memory in the resurrection plant Boea hygrometrica. e1009549页
作者:Run-Ze,Sun; Jie,Liu; Yuan-Yuan,Wang; Xin,Deng
18. Correction: Inference of past demography, dormancy and self-fertilization rates from whole genome sequence data. e1009504页
作者:Thibaut Paul Patrick,Sellinger; Diala,Abu Awad; Markus,Moest; Aurélien,Tellier
19. Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia. e1009482页
作者:Shizhen,Tang; Aron S,Buchman; Philip L,De Jager; David A,Bennett; Michael P,Epstein; Jingjing,Yang
20. Aicardi-Goutières syndrome-associated gene SAMHD1 preserves genome integrity by preventing R-loop formation at transcription-replication conflict regions. e1009523页
作者:Kiwon,Park; Jeongmin,Ryoo; Heena,Jeong; Minsu,Kim; Sungwon,Lee; Sung-Yeon,Hwang; Jiyoung,Ahn; Doyeon,Kim; Hyungseok C,Moon; Daehyun,Baek; Kwangsoo,Kim; Hye Yoon,Park; Kwangseog,Ahn
21. DNA methylation patterns expose variations in enhancer-chromatin modifications during embryonic stem cell differentiation. e1009498页
作者:Adi,Alajem; Hava,Roth; Sofia,Ratgauzer; Danny,Bavli; Alex,Motzik; Shlomtzion,Lahav; Itay,Peled; Oren,Ram
22. Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study. e1009525页
作者:Mark,Gormley; James,Yarmolinsky; Tom,Dudding; Kimberley,Burrows; Richard M,Martin; Steven,Thomas; Jessica,Tyrrell; Paul,Brennan; Miranda,Pring; Stefania,Boccia; Andrew F,Olshan; Brenda,Diergaarde; Rayjean J,Hung; Geoffrey,Liu; Danny,Legge; Eloiza H,Tajara; Patricia,Severino; Martin,Lacko; Andrew R,Ness; George,Davey Smith; Emma E,Vincent; Rebecca C,Richmond
24. Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae. e1009538页
作者:Kotchaphorn,Mangkalaphiban; Feng,He; Robin,Ganesan; Chan,Wu; Richard,Baker; Allan,Jacobson
25. The actin nucleation factors JMY and WHAMM enable a rapid Arp2/3 complex-mediated intrinsic pathway of apoptosis. e1009512页
作者:Virginia L,King; Nathan K,Leclair; Alyssa M,Coulter; Kenneth G,Campellone
26. Mobile Type VI secretion system loci of the gut Bacteroidales display extensive intra-ecosystem transfer, multi-species spread and geographical clustering. e1009541页
作者:Leonor,García-Bayona; Michael J,Coyne; Laurie E,Comstock
27. ARID1A regulates R-loop associated DNA replication stress. e1009238页
作者:Shuhe,Tsai; Louis-Alexandre,Fournier; Emily Yun-Chia,Chang; James P,Wells; Sean W,Minaker; Yi Dan,Zhu; Alan Ying-Hsu,Wang; Yemin,Wang; David G,Huntsman; Peter C,Stirling
29. The canonical α-SNAP is essential for gametophytic development in Arabidopsis. e1009505页
作者:Fei,Liu; Ji-Peng,Li; Lu-Shen,Li; Qi,Liu; Shan-Wei,Li; Ming-Lei,Song; Sha,Li; Yan,Zhang
30. A complex genetic architecture in zebrafish relatives Danio quagga and D. kyathit underlies development of stripes and spots. e1009364页
作者:Braedan M,McCluskey; Susumu,Uji; Joseph L,Mancusi; John H,Postlethwait; David M,Parichy
31. The RabGAP TBC-11 controls Argonaute localization for proper microRNA function in C. elegans. e1009511页
作者:Pascale,Michaud; Vivek Nilesh,Shah; Pauline,Adjibade; Francois,Houle; Miguel,Quévillon Huberdeau; Rachel,Rioux; Camille,Lavoie-Ouellet; Weifeng,Gu; Rachid,Mazroui; Martin J,Simard
32. Widespread imprinting of transposable elements and variable genes in the maize endosperm. e1009491页
作者:Sarah N,Anderson; Peng,Zhou; Kaitlin,Higgins; Yaniv,Brandvain; Nathan M,Springer
33. Subunit P60 of phosphatidylinositol 3-kinase promotes cell proliferation or apoptosis depending on its phosphorylation status. e1009514页
作者:Yu-Qin,Di; Yu-Meng,Zhao; Ke-Yan,Jin; Xiao-Fan,Zhao
34. Trehalose and α-glucan mediate distinct abiotic stress responses in Pseudomonas aeruginosa. e1009524页
作者:Stuart D,Woodcock; Karl,Syson; Richard H,Little; Danny,Ward; Despoina,Sifouna; James K M,Brown; Stephen,Bornemann; Jacob G,Malone
35. Intercellular viral spread and intracellular transposition of Drosophila gypsy. e1009535页
作者:Richard M,Keegan; Lillian R,Talbot; Yung-Heng,Chang; Michael J,Metzger; Josh,Dubnau
36. Virus-derived variation in diverse human genomes. e1009324页
作者:Shohei,Kojima; Anselmo Jiro,Kamada; Nicholas F,Parrish
37. CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury. e1009515页
作者:Marcus,Keatinge; Themistoklis M,Tsarouchas; Tahimina,Munir; Nicola J,Porter; Juan,Larraz; Davide,Gianni; Hui-Hsin,Tsai; Catherina G,Becker; David A,Lyons; Thomas,Becker
38. Tempo and mode in karyotype evolution revealed by a probabilistic model incorporating both chromosome number and morphology. e1009502页
39. Leveraging expression from multiple tissues using sparse canonical correlation analysis and aggregate tests improves the power of transcriptome-wide association studies. e1008973页
作者:Helian,Feng; Nicholas,Mancuso; Alexander,Gusev; Arunabha,Majumdar; Megan,Major; Bogdan,Pasaniuc; Peter,Kraft
40. Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease. e1009503页
作者:Connor A,Emdin; Mary E,Haas; Amit V,Khera; Krishna,Aragam; Mark,Chaffin; Derek,Klarin; George,Hindy; Lan,Jiang; Wei-Qi,Wei; Qiping,Feng; Juha,Karjalainen; Aki,Havulinna; Tuomo,Kiiskinen; Alexander,Bick; Diego,Ardissino; James G,Wilson; Heribert,Schunkert; Ruth,McPherson; Hugh,Watkins; Roberto,Elosua; Matthew J,Bown; Nilesh J,Samani; Usman,Baber; Jeanette,Erdmann; Namrata,Gupta; John,Danesh; Danish,Saleheen; Kyong-Mi,Chang; Marijana,Vujkovic; Ben,Voight; Scott,Damrauer; Julie,Lynch; David,Kaplan; Marina,Serper; Philip,Tsao; Million Veteran,Program; Josep,Mercader; Craig,Hanis; Mark,Daly; Joshua,Denny; Stacey,Gabriel; Sekar,Kathiresan
41. Pathways and signatures of mutagenesis at targeted DNA nicks. e1009329页
作者:Yinbo,Zhang; Luther,Davis; Nancy,Maizels
42. Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. e1009112页
作者:Lucilla,Pizzo; Micaela,Lasser; Tanzeen,Yusuff; Matthew,Jensen; Phoebe,Ingraham; Emily,Huber; Mayanglambam Dhruba,Singh; Connor,Monahan; Janani,Iyer; Inshya,Desai; Siddharth,Karthikeyan; Dagny J,Gould; Sneha,Yennawar; Alexis T,Weiner; Vijay Kumar,Pounraja; Arjun,Krishnan; Melissa M,Rolls; Laura Anne,Lowery; Santhosh,Girirajan
43. LuxT controls specific quorum-sensing-regulated behaviors in Vibrionaceae spp. via repression of qrr1, encoding a small regulatory RNA. e1009336页
作者:Michaela J,Eickhoff; Chenyi,Fei; Xiuliang,Huang; Bonnie L,Bassler
44. ANGPTL8 protein-truncating variant associated with lower serum triglycerides and risk of coronary disease. e1009501页
作者:Pyry,Helkkula; Tuomo,Kiiskinen; Aki S,Havulinna; Juha,Karjalainen; Seppo,Koskinen; Veikko,Salomaa; Mark J,Daly; Aarno,Palotie; Ida,Surakka; Samuli,Ripatti; FinnGen
45. Ionotropic Receptor-dependent cool cells control the transition of temperature preference in Drosophila larvae. e1009499页
作者:Jordan J,Tyrrell; Jackson T,Wilbourne; Alisa A,Omelchenko; Jin,Yoon; Lina,Ni
46. Identification of common predisposing loci to hematopoietic cancers in four dog breeds. e1009395页
作者:Benoît,Hédan; Édouard,Cadieu; Maud,Rimbault; Amaury,Vaysse; Caroline,Dufaure de Citres; Patrick,Devauchelle; Nadine,Botherel; Jérôme,Abadie; Pascale,Quignon; Thomas,Derrien; Catherine,André
47. Evolutionary dynamics of the human pseudoautosomal regions. e1009532页
作者:Bruno,Monteiro; Miguel,Arenas; Maria João,Prata; António,Amorim
48. Caenorhabditis elegans PTR/PTCHD PTR-18 promotes the clearance of extracellular hedgehog-related protein via endocytosis. e1009457页
作者:Hirohisa,Chiyoda; Masahiko,Kume; Carla Cadena,Del Castillo; Kenji,Kontani; Anne,Spang; Toshiaki,Katada; Masamitsu,Fukuyama
49. ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing. e1009439页
作者:Seungjae,Lee; Lu,Wei; Binglong,Zhang; Raeann,Goering; Sonali,Majumdar; Jiayu,Wen; J Matthew,Taliaferro; Eric C,Lai
50. Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis. e1009275页
作者:David,Mellis; Katherine A,Staines; Silvia,Peluso; Ioanna Ch,Georgiou; Natalie,Dora; Malgorzata,Kubiak; Rob,Van't Hof; Michela,Grillo; Colin,Farquharson; Elaine,Kinsella; Anna,Thornburn; Stuart H,Ralston; Donald M,Salter; Natalia A,Riobo-Del Galdo; Robert E,Hill; Mark,Ditzel
51. Dynamic post-transcriptional regulation by Mrn1 links cell wall homeostasis to mitochondrial structure and function. e1009521页
作者:Kendra,Reynaud; Molly,Brothers; Michael,Ly; Nicholas T,Ingolia
52. Coordinating the morphogenesis-differentiation balance by tweaking the cytokinin-gibberellin equilibrium. e1009537页
作者:Alon,Israeli; Yogev,Burko; Sharona,Shleizer-Burko; Iris Daphne,Zelnik; Noa,Sela; Mohammad R,Hajirezaei; Alisdair R,Fernie; Takayuki,Tohge; Naomi,Ori; Maya,Bar
53. Two transcriptionally distinct pathways drive female development in a reptile with both genetic and temperature dependent sex determination. e1009465页
作者:Sarah L,Whiteley; Clare E,Holleley; Susan,Wagner; James,Blackburn; Ira W,Deveson; Jennifer A,Marshall Graves; Arthur,Georges
54. Genome-wide proximity between RNA polymerase and DNA topoisomerase I supports transcription in Streptococcus pneumoniae. e1009542页
作者:María-José,Ferrándiz; Pablo,Hernández; Adela G,de la Campa
55. Correction: Genome-Wide Reprogramming of Transcript Architecture by Temperature Specifies the Developmental States of the Human Pathogen Histoplasma. e1009509页
作者:Sarah A,Gilmore; Mark,Voorhies; Dana,Gebhart; Anita,Sil
56. An insulator blocks access to enhancers by an illegitimate promoter, preventing repression by transcriptional interference. e1009536页
作者:Miki,Fujioka; Anastasiya,Nezdyur; James B,Jaynes
57. Mapping the degradation pathway of a disease-linked aspartoacylase variant. e1009539页
作者:Sarah K,Gersing; Yong,Wang; Martin,Grønbæk-Thygesen; Caroline,Kampmeyer; Lene,Clausen; Martin,Willemoës; Claes,Andréasson; Amelie,Stein; Kresten,Lindorff-Larsen; Rasmus,Hartmann-Petersen
58. Tissue specificity-aware TWAS (TSA-TWAS) framework identifies novel associations with metabolic, immunologic, and virologic traits in HIV-positive adults. e1009464页
作者:Binglan,Li; Yogasudha,Veturi; Anurag,Verma; Yuki,Bradford; Eric S,Daar; Roy M,Gulick; Sharon A,Riddler; Gregory K,Robbins; Jeffrey L,Lennox; David W,Haas; Marylyn D,Ritchie
59. Toxic Y chromosome: Increased repeat expression and age-associated heterochromatin loss in male Drosophila with a young Y chromosome. e1009438页
作者:Alison H,Nguyen; Doris,Bachtrog