• 医学文献
  • 知识库
  • 评价分析
  • 全部
  • 中外期刊
  • 学位
  • 会议
  • 专利
  • 成果
  • 标准
  • 法规
  • 临床诊疗知识库
  • 中医药知识库
  • 机构
  • 作者
热搜词:
换一批
论文 期刊
取消
高级检索

检索历史 清除

医学文献 >>
  • 全部
  • 中外期刊
  • 学位
  • 会议
  • 专利
  • 成果
  • 标准
  • 法规
知识库 >>
  • 临床诊疗知识库
  • 中医药知识库
评价分析 >>
  • 机构
  • 作者
热搜词:
换一批

杭州市某城市化区域居民血脂代谢异常率及其与其他代谢因素的相关性

Prevalence of dyslipidemia and correlation between blood lipid and metabolic factors among urbanized region residents in Hangzhou

摘要:

目的 了解杭州市江干区城市化区域居民血脂状况及相关代谢影响因素,为该区域的血脂异常防治提供依据.方法 采用随机整群抽样方法选取3个城市化社区≥18岁常住户籍居民共2 590例,调查分析不同性别、不同年龄组间的血脂代谢异常率;TC、TG、LDL-C、HDL-C水平分别与BMI、腰围、收缩压、舒张压、空腹血糖、糖化血红蛋白、尿酸水平进行Spearmam相关分析,并采用x2检验、x2趋势检验和非条件logistic回归分析方法分析血脂异常与超重或肥胖、高血压、高血糖、高尿酸血症的相关性.结果 总血脂代谢异常率60.0%(1 554/2 590),标化率为57.2%.高TC血症率为42.9%(1 111/2 590),标化率为40.5%,其中边缘升高率为31.7% (822/2 590),标化率为30.5%;升高率为11.2%(289/2 590),标化率为10.0%.高TG血症率为33.0%(855/2 590),标化率为30.7%,其中边缘升高率为15.3% (397/2 590),标化率为14.3%;升高率为17.7% (458/2 590),标化率为16.4%.高LDL-C血症率为30.4%(787/2 590),标化率为28.4%,其中边缘升高率22.9%(594/2 590),标化率为21.7%;升高率为7.5%(193/2 590),标化率6.7%.低HDL-C血症率为12.6%(327/2 590),标化率为12.8%.总血脂代谢异常率及各类型血脂代谢异常率在性别间比较差异均无统计学意义(均P>0.05).高TC血症、高TG血症、高LDL-C血症、总血脂代谢异常率均随年龄的增加而升高(趋势检验均P <0.01),而低HDL-C血症率未随年龄而有趋势变化(趋势检验P>0.05).Spearmam相关分析结果显示,TC、TG、LDL-C水平均与BMI、腰围、收缩压、舒张压、空腹血糖、糖化血红蛋白、尿酸水平呈正相关(均P<0.01),而HDL-C水平均与BMI、腰围、收缩压、舒张压、空腹血糖、糖化血红蛋白、尿酸呈负相关(均P<0.05).总血脂代谢异常率及各类型血脂代谢异常率均随BMI水平的升高呈上升趋势(趋势检验均P<0.01),各类型血脂代谢异常率在腰围、血压、血糖、血尿酸不同组(升高组和非升高组)间比较差异也均有统计学意义(均P< 0.05).非条件logistic回归分析显示,在校正年龄和性别因素后,超重或肥胖、高血压均是高TC血症和高LDL-C血症的危险因素,超重或肥胖、高尿酸血症是低HDL-C血症的危险因素,超重或肥胖、高血压、高血糖和高尿酸血症均为高TG血症和总血脂异常的危险因素.结论 城市化社区人群有较高的血脂代谢异常率,超重或肥胖、高血压、高血糖和高尿酸血症影响血脂代谢,需加强人群血脂异常的监测和综合防治.

更多
abstracts:

Objective To provide rationales for preventing and treating dyslipidemia by understanding the current status of lipids and related metabolic factors.Methods A total of 2 590 permanent residents aged ≥ 18 years were selected by random cluster sampling from three urbanized communities of Sijiqing Street.And the rate of abnormal lipid metabolism was calculated for different ages and genders.Spearman's correlation analyses were conducted for the levels of total cholesterol (TC),total triglyceride (TG),low density lipoprotein-cholesterol (LDL-C),high density lipoprotein-cholesterol (HDL-C),body mass index (BMI),waist circumference (WC),systolic blood pressure (SBP),diastolic blood pressure (DBP),fasting plasma glucose (FPG),glycated hemoglobin (HbA 1 c) and uric acid (UA) levels.Both x2 test and logisic regression were employed to examine the correlations between dyslipidemia and overweight/obesity,hypertension,hyperglycemia and hyperuricemia.Results ① The total rate of abnormal lipid metabolism was 60.0% (1 554/2 590) with a standardized rate of 57.2%.High TC rate was 42.9% (1 111/2 590) with a standardized rate of 40.5%.And the edge incremental rate was 31.7% (822/ 2 590),the standardized rate 30.5%,the incremental rate 11.2% (289/2 590) and the standardized rate 10.0%.High TG rate was 33.0% (855/2 590) with a standardized rate of 30.7%.And the edge incremental rate was 15.3% (397/2 590),the standardized rate 14.3%,the incremental rate 17.7% (458/2 590) and the standardized rate 16.4%.High LDL-C rate was 30.4% (787/2 590) with a standardized rate of 28.4%.And the edge incremental rate was 22.9% (594/2 590),the standardized rate 21.7%,the incremental rate 7.5% (193/2 590) and the standardized rate 6.7%.Low HDL-C rate was 12.6% (327/2 590) with a standardized rate of 12.8%.The rates of high TC,high TG,high LDL-C,low HDL-C and abnormal lipid metabolism among gender showed no statistically significant difference (P > 0.05);② For both males & females,high TC rate,high TG rate,high LDL-C rate and total rate of abnormal lipid metabolism increased with age (P < 0.01) while low HDL-C rate did not change with age (P > 0.05);③Spearman's correlation analysis showed that the levels of TC,TG and LDL-C were positively correlated with BMI,WC,SBP,DBP,FBG,HbA1C and UA (all P <0.01) while the level of HDL-C had negative correlations with BMI,WC,SBP,DBP,FBG,HbA1 c,and UA (all P < 0.05);④The total rate of abnormal lipid metabolism and various types of abnormal lipid metabolism increased with a rising level of BMI in the upward trend (trend test P < 0.01),various types of abnormal lipid metabolism rate between different groups (elevated & non-elevated) of blood pressure,glucose and uric acid also were statistically significant (all P < 0.05);⑤ Non-conditional logistic regression analysis showed that,after adjusting for age and gender,overweight or obesity and hypertension were risk factors of high TC and high LDL-C;overweight or obesity,hyperuricemia was a risk factor for low HDL-C;overweight or obesity,hypertension,hyperglycemia and hyperuricemia were risk factors for high TG and total abnormal blood lipid.Conclusions Urbanized community groups have a high rate of dyslipidemia.And abnormal lipid metabolism is affected by overweight or obesity,hypertension,hyperglycemia and hyperuricemia.The target population should be regularly monitored and comprehensively controlled.

More
  • 浏览:270
  • 下载:148

加载中!

相似文献

  • 中文期刊
  • 外文期刊
  • 学位论文
  • 会议论文

加载中!

加载中!

加载中!

加载中!

扩展文献

特别提示:本网站仅提供医学学术资源服务,不销售任何药品和器械,有关药品和器械的销售信息,请查阅其他网站。

  • 客服热线:4000-115-888 转3 (周一至周五:8:00至17:00)

  • |
  • 客服邮箱:yiyao@wanfangdata.com.cn

  • 违法和不良信息举报电话:4000-115-888,举报邮箱:problem@wanfangdata.com.cn,举报专区

官方微信
万方医学小程序
new翻译 充值 订阅 收藏 移动端

官方微信

万方医学小程序

使用
帮助
Alternate Text
调查问卷