Blockade of the extracellular signal-regulated kinase pathway induces marked G1 cell cycle arrest and apoptosis in tumor cells in which the pathway is constitutively activated: up-regulation of p27(Kip1).
作者:
Hoshino R [1]
;
Tanimura S ;
Watanabe K ;
Kataoka T ;
Kohno M
作者单位:
Laboratory of Cell Regulation, School of Pharmaceutical Sciences, Nagasaki University, 1-14, Bunkyo-machi, Nagasaki 852-8131, Japan.
[1]
期刊:
关键词:
Antineoplastic Agents;Apoptosis;G1 Phase;Mitogen Activated Protein Kinases antagonists and inhibitors;抗肿瘤药;脱噬作用;G1期;肿瘤
发布时间:
2013-11-21
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