PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription.
第一作者:
Tamotsu,Nishida
第一单位:
Division of Molecular Biology, School of Life Science, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Japan.
作者:
医学主题词
人类(Humans);连接酶类(Ligases);活化STAT的蛋白抑制物(Protein Inhibitors of Activated STAT);蛋白质类(Proteins);受体, 雄激素(Receptors, Androgen);阻遏蛋白质类(Repressor Proteins);小泛素相关修饰蛋白质类(Small Ubiquitin-Related Modifier Proteins);转录激活(Transcriptional Activation);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1074/jbc.M206741200
PMID
12177000
发布时间
2021-02-09
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