High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway.
第一作者:
Sun,Lin
第一单位:
Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611, USA.
作者:
医学主题词
动物(Animals);环AMP(Cyclic AMP);糖尿病肾病(Diabetic Nephropathies);纤连蛋白类(Fibronectins);葡萄糖(Glucose);肾(Kidney);血小板源性生长因子(Platelet-Derived Growth Factor);蛋白激酶C(Protein Kinase C);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);原癌基因蛋白质c-raf(Proto-Oncogene Proteins c-raf);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);转染(Transfection);rap GTP结合蛋白质类(rap GTP-Binding Proteins)
DOI
10.1074/jbc.M203957200
PMID
12196513
发布时间
2021-02-06
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