换一批Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the sigma receptor.
第一作者：
B R,de Costa
第一单位：
Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.
作者：
医学主题词
动物(Animals);乙胺类(Ethylamines);豚鼠(Guinea Pigs);男(雄)性(Male);吡咯烷类(Pyrrolidines);大鼠(Rats);大鼠, 近交系(Rats, Inbred Strains);受体, 阿片样(Receptors, Opioid);受体, Σ(Receptors, sigma);构效关系(Structure-Activity Relationship)
DOI
10.1021/jm00079a004
PMID
1310114
发布时间
2019-07-09
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