Increase of nuclear ceramide through caspase-3-dependent regulation of the "sphingomyelin cycle" in Fas-induced apoptosis.
第一作者:
Mitsumasa,Watanabe
第一单位:
Department of Hematology, Graduate School of Medicine, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
作者:
医学主题词
氨基酸氯甲基酮类(Amino Acid Chloromethyl Ketones);细胞凋亡(Apoptosis);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞核(Cell Nucleus);神经酰胺类(Ceramides);半胱氨酸蛋白酶抑制剂(Cysteine Proteinase Inhibitors);酶激活(Enzyme Activation);人类(Humans);Jurkat细胞(Jurkat Cells);原冰片烷类(Norbornanes);磷酸二酯酶抑制剂(Phosphodiesterase Inhibitors);鞘磷脂磷酸二酯酶(Sphingomyelin Phosphodiesterase);鞘磷脂类(Sphingomyelins);T淋巴细胞(T-Lymphocytes);硫代氨基甲酸酯类(Thiocarbamates);硫酮类(Thiones);转移酶类(其他取代磷酸族)(Transferases (Other Substituted Phosphate Groups))
DOI
10.1158/0008-5472.can-03-1383
PMID
14871831
发布时间
2020-12-08
- 浏览30
Cancer research
1000-7页
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