Hypothalamic pro-opiomelanocortin gene delivery ameliorates obesity and glucose intolerance in aged rats.
第一作者:
G,Li
第一单位:
Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, FL, USA.
作者:
医学主题词
脂肪组织, 棕色(Adipose Tissue, Brown);衰老(Aging);刺鼠相关蛋白质(Agouti-Related Protein);动物(Animals);体重(Body Weight);胆固醇(Cholesterol);依赖病毒(Dependovirus);进食(Eating);脂肪酸类, 非酯化(Fatty Acids, Nonesterified);遗传载体(Genetic Vectors);葡萄糖(Glucose);葡糖耐受不良(Glucose Intolerance);葡糖耐量试验(Glucose Tolerance Test);下丘脑(Hypothalamus);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);瘦素(Leptin);男(雄)性(Male);神经肽Y(Neuropeptide Y);肥胖症(Obesity);肽类激素(Peptide Hormones);前阿片黑素细胞皮质激素(Pro-Opiomelanocortin);大鼠(Rats);大鼠, 近交F344(Rats, Inbred F344);受体, 黑皮质素, 3型(Receptor, Melanocortin, Type 3);受体, 黑皮质素, 4型(Receptor, Melanocortin, Type 4);甘油三酯类(Triglycerides)
DOI
10.1007/s00125-005-1943-8
PMID
16205885
发布时间
2018-11-13
- 浏览44
Diabetologia
2376-85页
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