Combined targeting of epidermal growth factor receptor, signal transducer and activator of transcription-3, and Bcl-X(L) enhances antitumor effects in squamous cell carcinoma of the head and neck.
第一作者:
Amanda L,Boehm
第一单位:
Department of Pathology, University of Pittsburgh, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.
作者:
医学主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞系, 肿瘤(Cell Line, Tumor);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物释放系统(Drug Delivery Systems);女(雌)性(Female);头颈部肿瘤(Head and Neck Neoplasms);人类(Humans);小鼠(Mice);喹唑啉类(Quinazolines);STAT3转录因子(STAT3 Transcription Factor);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);bcl-X蛋白质(bcl-X Protein)
DOI
10.1124/mol.107.044636
PMID
18326051
发布时间
2025-02-13
- 浏览5
Molecular pharmacology
1632-42页
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