Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation.
第一作者:
Christoph J,Wruck
第一单位:
Department of Anatomy and Cell Biology, RWTH Aachen, Wendlingweg 2, 52074 Aachen, Germany. cwruck@ukaachen.de
作者:
医学主题词
淀粉样β肽类(Amyloid beta-Peptides);动物(Animals);剂量效应关系, 药物(Dose-Response Relationship, Drug);内酯类(Lactones);丝裂原活化蛋白激酶1(Mitogen-Activated Protein Kinase 1);丝裂原活化蛋白激酶3(Mitogen-Activated Protein Kinase 3);NF-E2相关因子2(NF-E2-Related Factor 2);神经元(Neurons);神经保护药(Neuroprotective Agents);PC12细胞(PC12 Cells);大鼠(Rats)
DOI
10.1124/mol.107.042499
PMID
18334601
发布时间
2025-02-13
- 浏览5
Molecular pharmacology
1785-95页
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