Ca(2+)/calmodulin-dependent protein kinase II promotes cell cycle progression by directly activating MEK1 and subsequently modulating p27 phosphorylation.
第一作者:
Nan,Li
第一单位:
Institute of Immunology and National Key Laboratory of Medical Immunology, Second Military Medical University, Shanghai 200433, China. Electronic address: linan@immunol.org.
作者:
医学主题词
氨基酸序列(Amino Acid Sequence);钙-钙调素依赖性蛋白激酶2型(Calcium-Calmodulin-Dependent Protein Kinase Type 2);细胞周期(Cell Cycle);细胞系, 肿瘤(Cell Line, Tumor);周期素依赖激酶抑制剂p27(Cyclin-Dependent Kinase Inhibitor p27);酶激活(Enzyme Activation);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);MAP激酶激酶1(MAP Kinase Kinase 1);分子序列数据(Molecular Sequence Data);磷酰化(Phosphorylation)
DOI
10.1074/jbc.M805483200
PMID
19056740
发布时间
2022-08-24
- 浏览33
The Journal of biological chemistry
3021-3027页
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