换一批CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.
第一作者：
Erin G,Reed-Geaghan
第一单位：
Department of Neurosciences, Center for Global Health and Diseases, Case Western Reserve University, Cleveland, Ohio 44106, USA.
作者：
主题词
淀粉样β肽类(Amyloid beta-Peptides);动物(Animals);细胞, 培养的(Cells, Cultured);巨噬细胞活化(Macrophage Activation);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);小神经胶质细胞(Microglia);NF-κB(NF-kappa B);吞噬作用(Phagocytosis);蛋白质结合(Protein Binding);活性氧(Reactive Oxygen Species);信号传导(Signal Transduction);Toll样受体2(Toll-Like Receptor 2);Toll样受体4(Toll-Like Receptor 4);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.1523/JNEUROSCI.3158-09.2009
PMID
19776284
发布时间
2025-05-29
- 浏览21
The Journal of neuroscience
11982-92页
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