换一批The class I HDAC inhibitor MGCD0103 induces cell cycle arrest and apoptosis in colon cancer initiating cells by upregulating Dickkopf-1 and non-canonical Wnt signaling.
第一作者：
Shaheen,Sikandar
第一单位：
Department of Medicine, University of California, Irvine, USA.
作者：
医学主题词
动物(Animals);细胞凋亡(Apoptosis);苯甲酰胺类(Benzamides);癌(Carcinoma);细胞周期(Cell Cycle);细胞转化, 肿瘤(Cell Transformation, Neoplastic);细胞, 培养的(Cells, Cultured);结肠肿瘤(Colonic Neoplasms);药物评价, 临床前(Drug Evaluation, Preclinical);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HT29细胞(HT29 Cells);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);人类(Humans);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);小鼠(Mice);肿瘤干细胞(Neoplastic Stem Cells);嘧啶类(Pyrimidines);信号传导(Signal Transduction);增量调节(Up-Regulation);Wnt蛋白质类(Wnt Proteins)
DOI
10.18632/oncotarget.194
PMID
21317455
发布时间
2025-05-29
- 浏览105
Oncotarget
596-605页
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