R5-SHIV induces multiple defects in T cell function during early infection of rhesus macaques including accumulation of T reg cells in lymph nodes.
第一作者:
Michael,Santosuosso
第一单位:
Infectious Diseases Medicine Division, Vaccine and Immunotherapy Center, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America.
作者:
主题词
动物(Animals);抗体特异性(Antibody Specificity);抗原, CD(Antigens, CD);细胞死亡(Cell Death);趋化作用(Chemotaxis);基因产物, gag(Gene Products, gag);HIV包膜蛋白质gp120(HIV Envelope Protein gp120);人类(Humans);淋巴结(Lymph Nodes);猕猴(Macaca mulatta);黏膜(Mucous Membrane);受体, CCR5(Receptors, CCR5);受体, G-蛋白偶联(Receptors, G-Protein-Coupled);猴获得性免疫缺陷综合征(Simian Acquired Immunodeficiency Syndrome);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);时间因素(Time Factors)
DOI
10.1371/journal.pone.0018465
PMID
21483689
发布时间
2021-10-20
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