Rgs2 mediates pro-angiogenic function of myeloid derived suppressor cells in the tumor microenvironment via upregulation of MCP-1.
第一作者:
Kimberly C,Boelte
第一单位:
Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
作者:
主题词
动物(Animals);细胞死亡(Cell Death);细胞分化(Cell Differentiation);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);趋化因子CCL2(Chemokine CCL2);内皮细胞(Endothelial Cells);基因缺失(Gene Deletion);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);髓系细胞(Myeloid Cells);肿瘤(Neoplasms);新生血管化, 病理性(Neovascularization, Pathologic);RGS蛋白质类(RGS Proteins);信号传导(Signal Transduction);肿瘤微环境(Tumor Microenvironment);增量调节(Up-Regulation)
DOI
10.1371/journal.pone.0018534
PMID
21494556
发布时间
2021-10-20
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