Neonatal exposure to single doses of estradiol or testosterone programs ovarian follicular development-modified hypothalamic neurotransmitters and causes polycystic ovary during adulthood in the rat.
第一作者:
Ramón,Sotomayor-Zárate
第一单位:
Laboratory of Neurobiochemistry, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Independencia, Santiago, Chile.
作者:
医学主题词
年龄因素(Age Factors);衰老(Aging);动物(Animals);动物, 新生(Animals, Newborn);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物评价, 临床前(Drug Evaluation, Preclinical);雌二醇(Estradiol);女(雌)性(Female);下丘脑激素类(Hypothalamic Hormones);下丘脑(Hypothalamus);神经递质药(Neurotransmitter Agents);卵泡(Ovarian Follicle);多囊卵巢综合征(Polycystic Ovary Syndrome);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);突触传递(Synaptic Transmission);睾酮(Testosterone);下丘脑腹内侧核(Ventromedial Hypothalamic Nucleus)
DOI
10.1016/j.fertnstert.2011.09.011
PMID
21982285
发布时间
2013-11-21
- 浏览35
Fertility and sterility
1490-6页
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