换一批
换一批Small molecule inhibitors of the LEDGF site of human immunodeficiency virus integrase identified by fragment screening and structure based design.
作者：
主题词
结合部位(Binding Sites);细胞系(Cell Line);结晶学, X线(Crystallography, X-Ray);药物设计(Drug Design);酶抑制剂(Enzyme Inhibitors);HIV(HIV);HIV整合酶(HIV Integrase);人类(Humans);固定化蛋白质类(Immobilized Proteins);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);模型, 分子(Models, Molecular);肽碎片(Peptide Fragments);小分子化合物库(Small Molecule Libraries);构效关系(Structure-Activity Relationship);表面等离激元(Surface Plasmon Resonance)
DOI
10.1371/journal.pone.0040147
PMID
22808106
发布时间
2024-03-17
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