Role of microRNA-182 in posterior uveal melanoma: regulation of tumor development through MITF, BCL2 and cyclin D2.
作者:
主题词
3'非翻译区(3' Untranslated Regions);细胞系, 肿瘤(Cell Line, Tumor);细胞周期蛋白D2(Cyclin D2);减量调节(Down-Regulation);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因, 肿瘤抑制(Genes, Tumor Suppressor);人类(Humans);MAP激酶信号系统(MAP Kinase Signaling System);男(雄)性(Male);黑色素瘤(Melanoma);微RNAs(MicroRNAs);小眼畸形相关转录因子(Microphthalmia-Associated Transcription Factor);丝裂原活化蛋白激酶1(Mitogen-Activated Protein Kinase 1);丝裂原活化蛋白激酶3(Mitogen-Activated Protein Kinase 3);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);RNA, 肿瘤(RNA, Neoplasm);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);葡萄膜肿瘤(Uveal Neoplasms)
DOI
10.1371/journal.pone.0040967
PMID
22848417
发布时间
2021-10-21
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