The single crystal X-ray structure of β-hematin DMSO solvate grown in the presence of chloroquine, a β-hematin growth-rate inhibitor.
第一作者:
Johandie,Gildenhuys
第一单位:
Department of Chemistry and Polymer Science, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.
作者:
医学主题词
动物(Animals);氯喹(Chloroquine);结晶学, X线(Crystallography, X-Ray);二甲亚砜(Dimethyl Sulfoxide);剂量效应关系, 药物(Dose-Response Relationship, Drug);血红素蛋白类(Hemeproteins);动力学(Kinetics);模型, 分子(Models, Molecular);分子结构(Molecular Structure);溶液(Solutions);构效关系(Structure-Activity Relationship);猪(Swine)
DOI
10.1021/ja308741e
PMID
23253048
发布时间
2021-10-21
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