换一批Design, synthesis and biological screening of some pyridinylpyrazole and pyridinylisoxazole derivatives as potential anti-inflammatory, analgesic, antipyretic and antimicrobial agents.
第一作者：
Soad A M,El-Hawash
第一单位：
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Alexandria, Egypt. soadhawash@yahoo.com.
作者：
医学主题词
镇痛药(Analgesics);动物(Animals);抗菌药(Anti-Bacterial Agents);消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);退热药(Antipyretics);环氧化酶2(Cyclooxygenase 2);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物设计(Drug Design);水肿(Edema);大肠杆菌(Escherichia coli);甲醛(Formaldehyde);异恶唑类(Isoxazoles);男(雄)性(Male);微生物敏感性试验(Microbial Sensitivity Tests);模型, 分子(Models, Molecular);分子结构(Molecular Structure);铜绿假单胞菌(Pseudomonas aeruginosa);吡唑类(Pyrazoles);吡啶类(Pyridines);大鼠(Rats);大鼠, Wistar(Rats, Wistar);构效关系(Structure-Activity Relationship)
DOI
10.2174/15734064113096660044
PMID
24032466
发布时间
2019-10-27
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