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Intranuclear interactomic inhibition of FoxP3 suppresses functions of Treg cells.

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第一作者： Jong-Hyun,Park

第一单位： Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

作者： Jong-Hyun,Park ^[1] ; Ji Seung,Ko ^[2] ; Yoonchul,Shin ^[1] ; Jen Young,Cho ^[3] ; Han-ah,Oh ^[1] ; Alfred L M,Bothwell ^[4] ; Sang-Kyou,Lee

作者单位： Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea. ^[1] Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea. ^[2] Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06519, USA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA. ^[3] Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea. Electronic address: sjrlee@yonsei.ac.kr. ^[4]

关键词 Cancer immunotherapy FoxP3 Intranuclear interactomic inhibitor of transcription factor Protein transduction domain Regulatory T cells