Identification of a novel gene for diabetic traits in rats, mice, and humans.

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第一作者： Shirng-Wern,Tsaih

第一单位： Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.

作者： Shirng-Wern,Tsaih ^[1] ; Katie,Holl ^[2] ; Shuang,Jia ^[2] ; Mary,Kaldunski ^[2] ; Michael,Tschannen ^[1] ; Hong,He ^[2] ; Jaime Wendt,Andrae ^[1] ; Shun-Hua,Li ^[3] ; Alex,Stoddard ^[2] ; Andrew,Wiederhold ^[3] ; John,Parrington ^[4] ; Margarida,Ruas da Silva ^[4] ; Antony,Galione ^[4] ; James,Meigs ^[5] ; Meta-Analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) Investigators ^[2] ; Raymond G,Hoffmann ^[2] ; Pippa,Simpson ^[2] ; Howard,Jacob ^[2] ; Martin,Hessner ^[6] ; Leah C,Solberg Woods

作者单位： Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226. ^[1] Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226. ^[2] Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226. ^[3] Department of Pharmacology, University of Oxford, Oxford, OX1 3QT, United Kingdom. ^[4] Department of Medicine, Harvard Medical School, General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts 02114. ^[5] Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 lsolberg@mcw.edu. ^[6]

关键词 MPP Multiparent Advanced Generation Inter-Cross (MAGIC)Multiparental populations Tpcn2 expression QTL mapping glucose heterogeneous stock rats insulin type 2 diabetes