首页> Bioorganic & medicinal chemistry letters> ΔF508-CFTR correctors: synthesis and evaluation of thiazole-tethered imidazolones, oxazoles, oxadiazoles, and thiadiazoles.

ΔF508-CFTR correctors: synthesis and evaluation of thiazole-tethered imidazolones, oxazoles, oxadiazoles, and thiadiazoles.

导出 OA

翻译打印收藏纠错

第一作者： Long,Ye

第一单位： Department of Chemistry, College of Chemical Engineering and Technology, Wuhan University of Science and Technology, Wuhan, Hubei 430081, PR China. Electronic address: yelong@wust.edu.cn.

作者： Long,Ye ^[1] ; Bao,Hu ^[2] ; Faris,El-Badri ^[3] ; Brandi M,Hudson ^[3] ; Puay-Wah,Phuan ^[4] ; A S,Verkman ^[4] ; Dean J,Tantillo ^[3] ; Mark J,Kurth ^[5]

作者单位： Department of Chemistry, College of Chemical Engineering and Technology, Wuhan University of Science and Technology, Wuhan, Hubei 430081, PR China. Electronic address: yelong@wust.edu.cn. ^[1] Department of Chemistry, College of Chemical Engineering and Technology, Wuhan University of Science and Technology, Wuhan, Hubei 430081, PR China. ^[2] Department of Chemistry, University of California, One Shields Ave, Davis, CA 95616, United States. ^[3] Department of Medicine, University of California, San Francisco, CA 94143-0521, United States; Department Physiology, University of California, San Francisco, CA 94143-0521, United States. ^[4] Department of Chemistry, University of California, One Shields Ave, Davis, CA 95616, United States. Electronic address: mjkurth@ucdavis.edu. ^[5]

关键词 C,C-linked bisazoles Correctors Cystic fibrosis Transmembrane regulator