首页> Yonsei medical journal> In silico Screening of Chemical Libraries to Develop Inhibitors That Hamper the Interaction of PCSK9 with the LDL Receptor.

In silico Screening of Chemical Libraries to Develop Inhibitors That Hamper the Interaction of PCSK9 with the LDL Receptor.

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第一作者： Dong-Kook,Min

第一单位： Department of Biochemistry and Molecular Biology, Institute of Genetic Science, Integrated Genomic Research Center for Metabolic Regulation, Yonsei University College of Medicine, Seoul, Korea.;Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.

作者： Dong-Kook,Min ^[1] ; Hyun-Sook,Lee ^[2] ; Narae,Lee ^[1] ; Chan Joo,Lee ^[1] ; Hyun Joo,Song ^[2] ; Ga Eul,Yang ^[2] ; Dojun,Yoon ^[3] ; Sahng Wook,Park ^[4]

作者单位： Department of Biochemistry and Molecular Biology, Institute of Genetic Science, Integrated Genomic Research Center for Metabolic Regulation, Yonsei University College of Medicine, Seoul, Korea.;Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea. ^[1] Department of Biochemistry and Molecular Biology, Institute of Genetic Science, Integrated Genomic Research Center for Metabolic Regulation, Yonsei University College of Medicine, Seoul, Korea. ^[2] Department of Biochemistry, Catholic Kwandong University College of Medicine, Gangneung, Korea. ^[3] Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.;Department of Biochemistry and Molecular Biology, Institute of Genetic Science, Integrated Genomic Research Center for Metabolic Regulation, Yonsei University College of Medicine, Seoul, Korea. swpark64@yuhs.ac. ^[4]

关键词 LDL receptor PCSK9 hypercholesterolemia in silico inhibitor protein-protein interaction