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Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.

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第一作者： Helena,Ågerstam

第一单位： Department of Clinical Genetics, Lund University, 22184 Lund, Sweden; helena.agerstam@med.lu.se thoas.fioretos@med.lu.se.

作者： Helena,Ågerstam ^[1] ; Christine,Karlsson ^[2] ; Nils,Hansen ^[2] ; Carl,Sandén ^[2] ; Maria,Askmyr ^[2] ; Sofia,von Palffy ^[2] ; Carl,Högberg ^[2] ; Marianne,Rissler ^[2] ; Mark,Wunderlich ^[3] ; Gunnar,Juliusson ^[4] ; Johan,Richter ^[4] ; Kjell,Sjöström ^[5] ; Ravi,Bhatia ^[6] ; James C,Mulloy ^[3] ; Marcus,Järås ^[2] ; Thoas,Fioretos ^[1]

作者单位： Department of Clinical Genetics, Lund University, 22184 Lund, Sweden; helena.agerstam@med.lu.se thoas.fioretos@med.lu.se. ^[1] Department of Clinical Genetics, Lund University, 22184 Lund, Sweden; ^[2] Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; ^[3] Department of Hematology and Vascular Disorders, Skåne University Hospital, 22185 Lund, Sweden; ^[4] Innovagen AB, 22370 Lund, Sweden; ^[5] Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294. ^[6]

关键词 AML IL1RAP antibody immunotherapy leukemia