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Chimeric PD-1:28 Receptor Upgrades Low-Avidity T cells and Restores Effector Function of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy.

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第一作者： Ramona,Schlenker

第一单位： Institute of Molecular Immunology, Helmholtz Center Munich, Munich, Germany.

作者： Ramona,Schlenker ^[1] ; Luis Felipe,Olguín-Contreras ^[2] ; Matthias,Leisegang ^[3] ; Julia,Schnappinger ^[2] ; Anja,Disovic ^[2] ; Svenja,Rühland ^[4] ; Peter J,Nelson ^[5] ; Heinrich,Leonhardt ^[6] ; Hartmann,Harz ^[6] ; Susanne,Wilde ^[7] ; Dolores J,Schendel ^[7] ; Wolfgang,Uckert ^[8] ; Gerald,Willimsky ^[9] ; Elfriede,Noessner ^[10]

作者单位： Institute of Molecular Immunology, Helmholtz Center Munich, Munich, Germany. ^[1] Institute of Molecular Immunology, Helmholtz Center Munich, Munich, Germany.;Immunoanalytics Research Group Tissue Control of Immunocytes & Core Facility, Helmholtz Center Munich, Munich, Germany. ^[2] Institute of Immunology, Charité, Campus Buch, Berlin, Germany.;Berlin Institute of Health (BIH), Berlin, Germany. ^[3] Ludwig-Maximilian University Munich, Medizinische Klinik und Poliklinik IV, Munich, Germany.;Department of Biology II and Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilian University Munich, Munich, Germany. ^[4] Ludwig-Maximilian University Munich, Medizinische Klinik und Poliklinik IV, Munich, Germany. ^[5] Department of Biology II and Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilian University Munich, Munich, Germany. ^[6] Medigene Immunotherapies GmbH, Munich, Germany. ^[7] Max Delbrück Center for Molecular Medicine, Berlin, Germany.;Institute of Biology, Humboldt University Berlin, Berlin, Germany. ^[8] Institute of Immunology, Charité, Campus Buch, Berlin, Germany.;German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[9] Institute of Molecular Immunology, Helmholtz Center Munich, Munich, Germany. noessner@helmholtz-muenchen.de.;Immunoanalytics Research Group Tissue Control of Immunocytes & Core Facility, Helmholtz Center Munich, Munich, Germany. ^[10]