Impaired insulin/IGF-1 is responsible for diabetic gastroparesis by damaging myenteric cholinergic neurones and interstitial cells of Cajal.
第一作者:
Shu,Yang
第一单位:
Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, P.R. China.;Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing 100069, P.R. China.;Department of Histology and Embryology, Logistics University of Chinese People's Armed Police Force, Tianjin 300162, P.R. China.
作者:
医学主题词
动物(Animals);抗原, CD(Antigens, CD);胆碱O-乙酰转移酶(Choline O-Acetyltransferase);糖尿病并发症(Diabetes Complications);疾病模型, 动物(Disease Models, Animal);胃肌轻瘫(Gastroparesis);基因表达调控(Gene Expression Regulation);人类(Humans);肌醇(Inositol);胰岛素(Insulin);胰岛素样生长因子Ⅰ(Insulin-Like Growth Factor I);Cajal小肠细胞(Interstitial Cells of Cajal);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);肌, 平滑(Muscle, Smooth);受体, IGF1型(Receptor, IGF Type 1);受体, 胰岛素(Receptor, Insulin);干细胞因子(Stem Cell Factor)
DOI
10.1042/BSR20170776
PMID
28931726
发布时间
2018-11-13
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