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Molecular Signature of Asthma-Enhanced Sensitivity to CuO Nanoparticle Aerosols from 3D Cell Model.

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第一作者： Ingeborg,Kooter

第一单位： The Netherlands Organization for Applied Scientific Research, TNO , P.O. Box 80015, Utrecht 3584 CB , The Netherlands.

作者： Ingeborg,Kooter ^[1] ; Marit,Ilves ^[2] ; Mariska,Gröllers-Mulderij ^[1] ; Evert,Duistermaat ^[3] ; Peter C,Tromp ^[1] ; Frieke,Kuper ^[1] ; Pia,Kinaret ^[4] ; Kai,Savolainen ^[5] ; Dario,Greco ^[4] ; Piia,Karisola ^[2] ; Joseph,Ndika ^[2] ; Harri,Alenius ^[6]

作者单位： The Netherlands Organization for Applied Scientific Research, TNO , P.O. Box 80015, Utrecht 3584 CB , The Netherlands. ^[1] Human Microbiome Research, Faculty of Medicine , University of Helsinki , P.O. Box 21, Helsinki 00290 , Finland. ^[2] Triskelion B.V. , P.O. Box 844, Zeist 3704 HE , The Netherlands. ^[3] Faculty of Medicine and Life Sciences , University of Tampere , Tampere FI-33014 , Finland.;Institute of Biotechnology , University of Helsinki , P.O. Box 56, Helsinki 00014 , Finland. ^[4] Finnish Institute of Occupational Health , P.O. Box 40, Helsinki 00014 , Finland. ^[5] Human Microbiome Research, Faculty of Medicine , University of Helsinki , P.O. Box 21, Helsinki 00290 , Finland.;Institute of Environmental Medicine , Karolinska Institutet , P.O. Box 210, Stockholm SE-17176 , Sweden. ^[6]

关键词 3d human bronchial epithelial cells air?liquid interface and transcriptomics asthma copper(II) oxide nanoparticles

医学主题词气雾剂(Aerosols);哮喘(Asthma);细胞, 培养的(Cells, Cultured);铜(Copper);人类(Humans);金属纳米粒子(Metal Nanoparticles);呼吸道黏膜(Respiratory Mucosa)

DOI 10.1021/acsnano.9b01823

PMID 31188557

发布时间 2024-07-23

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