首页> Journal of Alzheimer's disease : JAD> Quantitative Gradient Echo MRI Identifies Dark Matter as a New Imaging Biomarker of Neurodegeneration that Precedes Tisssue Atrophy in Early Alzheimer's Disease.

Quantitative Gradient Echo MRI Identifies Dark Matter as a New Imaging Biomarker of Neurodegeneration that Precedes Tisssue Atrophy in Early Alzheimer's Disease.

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第一作者： Satya V V N,Kothapalli

第一单位： Department of Radiology, Washington University in St. Louis, St. Louis, MO, USA.

作者： Satya V V N,Kothapalli ^[1] ; Tammie L,Benzinger ^[2] ; Andrew J,Aschenbrenner ^[3] ; Richard J,Perrin ^[4] ; Charles F,Hildebolt ^[1] ; Manu S,Goyal ^[5] ; Anne M,Fagan ^[6] ; Marcus E,Raichle ^[7] ; John C,Morris ^[3] ; Dmitriy A,Yablonskiy ^[8]

作者单位： Department of Radiology, Washington University in St. Louis, St. Louis, MO, USA. ^[1] Department of Radiology, Washington University in St. Louis, St. Louis, MO, USA.;Knight Alzheimer Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA. ^[2] Knight Alzheimer Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.;Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA. ^[3] Knight Alzheimer Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.;Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.;Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.;The Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO, USA. ^[4] Department of Radiology, Washington University in St. Louis, St. Louis, MO, USA.;Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA. ^[5] Knight Alzheimer Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.;Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.;The Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO, USA. ^[6] Department of Radiology, Washington University in St. Louis, St. Louis, MO, USA.;Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.;The Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO, USA. ^[7] Department of Radiology, Washington University in St. Louis, St. Louis, MO, USA.;Knight Alzheimer Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.;The Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO, USA. ^[8]

关键词 Alzheimer’s disease brain atrophy cognitive impairment hippocampal subfields hippocampus magnetic resonance imaging neurodegeneration quantitative Gradient Recalled Echo