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The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms.

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第一作者: Mohammad Nafees,Ansari
第一单位: Amity Institute of Integrative Sciences and Health, Amity University Haryana, Gurgaon, Haryana, India.;National Institute of Immunology, New Delhi, India.
作者单位: Amity Institute of Integrative Sciences and Health, Amity University Haryana, Gurgaon, Haryana, India.;National Institute of Immunology, New Delhi, India. [1] Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, Haryana, India. [2] Amity Institute of Integrative Sciences and Health, Amity University Haryana, Gurgaon, Haryana, India. [3] Koita Centre for Digital Health-Ashoka, Trivedi School of Biosciences, Ashoka University, Sonipat, India. [4] National Institute of Immunology, New Delhi, India. [5] Division of Molecular Medicine, St. Johns Research Institute, St Johns National Academy of Health Sciences, Bangalore, Karnataka, India.;Centre for Doctoral Studies, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India. [6] Tata Medical Center, Kolkata, West Bengal, India. [7] Department of Surgical Oncology, BRA-Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India. [8] Division of Molecular Medicine, St. Johns Research Institute, St Johns National Academy of Health Sciences, Bangalore, Karnataka, India. [9] Amity Institute of Integrative Sciences and Health, Amity University Haryana, Gurgaon, Haryana, India.;Koita Centre for Digital Health-Ashoka, Trivedi School of Biosciences, Ashoka University, Sonipat, India. [10]
DOI 10.1371/journal.pbio.3003362
PMID 40934285
发布时间 2025-09-15
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