换一批The cytostatic activity of 5-(1-azidovinyl)-2'-deoxyuridine (AzVDU) against herpes simplex virus thymidine kinase gene-transfected FM3A cells is due to inhibition of thymidylate synthase and enhanced by UV light (lambda = 254 nm) exposure.
第一作者：
J,Balzarini
第一单位：
Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium.
作者：
医学主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);抗病毒药(Antiviral Agents);叠氮化合物(Azides);细胞分裂(Cell Division);脱氧尿苷(Deoxyuridine);疱疹病毒3型, 人(Herpesvirus 3, Human);乳房肿瘤, 实验性(Mammary Neoplasms, Experimental);小鼠(Mice);小鼠, 近交C3H(Mice, Inbred C3H);分子结构(Molecular Structure);重组蛋白质类(Recombinant Proteins);单纯疱疹病毒属(Simplexvirus);构效关系(Structure-Activity Relationship);胸苷激酶(Thymidine Kinase);转染(Transfection);肿瘤细胞, 培养的(Tumor Cells, Cultured);病毒复制(Virus Replication)
DOI
10.1016/0014-5793(95)00994-k
PMID
7589430
发布时间
2019-06-21
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FEBS letters
41-4页
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