Thymocyte contact or monoclonal antibody-mediated clustering of 3beta1 or 6beta4 integrins activate interleukin-6 (IL-6) transcription factors (NF-kappaB and NF-IL6) and IL-6 production in human thymic epithelial cells.
第一作者:
D,Ramarli
第一单位:
Institute of Immunology and Infectious Diseases, University of Verona, Verona, Italy. dunia@borgoroma.univr.it>
作者:
医学主题词
抗体, 单克隆(Antibodies, Monoclonal);抗原, CD(Antigens, CD);抗原, 表面(Antigens, Surface);CCAAT增强子结合蛋白质δ(CCAAT-Enhancer-Binding Protein-delta);CCAAT增强子结合蛋白类(CCAAT-Enhancer-Binding Proteins);细胞黏附(Cell Adhesion);细胞间通讯(Cell Communication);细胞分化(Cell Differentiation);细胞, 培养的(Cells, Cultured);儿童, 学龄前(Child, Preschool);共同培养技术(Coculture Techniques);DNA结合蛋白质类(DNA-Binding Proteins);二聚作用(Dimerization);上皮细胞(Epithelial Cells);基因表达调控, 发育期(Gene Expression Regulation, Developmental);人类(Humans);婴儿(Infant);整合素α3β1(Integrin alpha3beta1);整合素α6β4(Integrin alpha6beta4);整合素β4(Integrin beta4);整合素类(Integrins);白细胞介素6(Interleukin-6);配体(Ligands);NF-κB(NF-kappa B);核蛋白质类(Nuclear Proteins);受体聚集(Receptor Aggregation);胸腺(Thymus Gland);转录因子(Transcription Factors);转录, 遗传(Transcription, Genetic)
PMID
9808569
发布时间
2025-05-29
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