摘要目的:探讨血清泌乳素水平对浆细胞乳腺炎治疗效果的临床价值。方法:回顾性分析2014年9月至2018年9月在某省级人民医院收治的病史资料完整的51例浆细胞乳腺炎患者，均于术前中西医联合药物治疗3～6个月后行病灶清除术，并出院随访1个月及以上。于治疗前、手术前分别检测血清泌乳素（PRL）水平和治疗前后PRL水平对伤口I期愈合率、术后总引流量和病情复发情况的影响。结果:51例确诊浆细胞乳腺炎患者治疗前后分别有62.7%（32/51）和41.2%（21/51）的患者PRL高于正常水平，治疗后高PRL者少于治疗前（ P<0.05）。不同PRL水平患者术后引流量和伤口I期愈合率比较差异无统计学意义，但PRL水平升高患者复发率高（ P<0.05）。 结论:浆细胞乳腺炎患者行中西医治疗后，高PRL患者明显减少。高PRL患者术后复发的风险增大。

abstractsObjective:To investigate the clinical value of serum prolactin level in the treatment effect of plasma cell mastitis.Methods:51 cases of plasma cell mastitis treated in a provincial people’s hospital from September 2014 to September 2018 were retrospectively analyzed. All of them received traditional Chinese medicine and western medicine treatment for 3-6 months before focal debridement, and were followed up for more than 1 month. The serum prolactin level was detected before and after treatment, and the effect of serum prolactin level on degree I wound healing rate, total postoperative drainage volume, and disease recurrence were evaluated.Results:There were 32 cases (62.7%) of increased prolactin level in the 51 patients before treatment, and 21 cases (41.2%) after treatment, the rate was decreased after treatment ( P<0.05). There were no statistically significant differences in postoperative drainage volume and degree I wound healing rate between patients with different prolactin levels, but the recurrence rate of patients with increased prolactin level was higher ( P<0.05). Conclusion:After traditional Chinese medicine and western medicine treatment, patients with increased prolactin level were significantly reduced. Patients with increased prolactin level had an increased risk of postoperative recurrence.