摘要新生儿围手术期血糖水平易受多种因素影响,一旦发生血糖紊乱,可能会导致预后不良,所以术中进行正确的血糖管理在新生儿麻醉领域一直备受关注.新生儿,尤其是早产儿,术中无论血糖过高还是过低均会导致大脑神经功能受损.为保证围手术期输液的安全性和有效性,术中给予含低浓度葡萄糖的等渗溶液,及时调整滴注速度,同时进行密切的血糖监测,可以维持血糖水平稳定,改善患儿预后.该文从新生儿围手术期血糖水平的影响因素、血糖紊乱的危害以及含糖液体的临床使用等方面进行综述.

abstractsThe perioperative blood glucose levels are susceptible to a variety of factors in newborns.If dysglycemia occurs,it is highly likely to lead to adverse clinical outcomes.Therefore,blood glucose management properly during operation has drawn great attention in the field of neonatal anesthesia.Neonates,especially premature infants,would have impaired neurological functions,once they develop hyperglycemia or hypoglycemia during surgery.Recent studies have shown that intraoperative administration of isotonic solution containing low concentrations of dextrose,close monitoring of blood glucose and promptly adjustment of the infusion rate can improve safety and prognosis.This review describes the influencing factors of perioperative blood glucose levels,the damage of dysglycemia and the effectiveness of dextrose-containing fluid in neonates.