摘要肾移植术后BK病毒感染与BK病毒相关性肾病及移植肾失功风险增加有关,然而BK病毒感染缺乏有效的预防措施及抗病毒药物,已成为移植肾失功的一大原因.因此术后早期监测BK病毒载量、调整免疫抑制方案、降低免疫抑制剂药量及辅助加用抗病毒药物尤为重要.该文就肾移植术后BK病毒感染的研究进展进行综述.
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abstractsBK virus infection after renal transplantation is associated with the increased risk of BK virus-associated nephropathy and graft loss.However,the lack of effective preventive measures and antiviral drugs has become a major cause of kidney transplantation failure.Therefore,early monitoring of BK virus load after kidney transplantation,adjustment of inhibition regimens,reduction of immunosuppressive drugs and adjuvant antiviral drugs are particularly important.The progress on BK virus-associated nephropathy after kidney transplantation is reviewed in the article.
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