摘要COPD持续性呼吸症状和气流受限为特点,随着疾病的发展,患者的生活质量将受到严重影响.目前COPD尚无特效的药物治疗,支气管镜介入治疗以其症状改善明显、并发症少等优点,为COPD的治疗带来了新的希望.支气管镜介入治疗包括支气管镜单向阀、聚合物肺减容术、支气管镜热蒸汽消融术、弹簧圈肺减容术、气道旁路支架术和去神经治疗.本文从这6种技术的原理、机制、临床试验、并发症方面综述COPD支气管镜介入治疗进展.

abstractsCOPD is characterized by persistent respiratory symptoms and airflow limitation.With the progression of the disease,patients' life quality will be affected severely.While there is no powerful drug available for COPD at present,the interventional therapy of bronchoscope,with its advantages of significantly improved symptoms and fewer complications,has brought new hope for the treatment of COPD.Bronchoscopic interventional therapy includes one-way endobronchial valves(EBV),polymeric lung volume reduction (PLVR),bronchoscopic heat vapor ablation (BTVA),lung volume reduction coils (LVRC),airway bypass stent (ABS) and targeted lung denervation (TLD).This paper provides an overview of the advances in interventional treatment of bronchoscope in chronic obstructive pulmonary diseases by analysing principles,mechanisms,clinical trials andcomplications of these six techniques.