换一批摘要周细胞位于脑毛细血管内皮细胞、星形胶质细胞和神经元之间，具有维持血脑屏障完整性、调节脑血流量等多种功能。周细胞丢失可导致脑微循环功能障碍和血脑屏障破坏等病理过程，并与多种疾病有关，但目前其与脑小血管病的相关性研究较少。文章主要对周细胞在脑小血管病发病机制中的作用进行了综述。
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abstractsPericytes are located between capillary endothelial cells, astrocytes and neurons. They have many functions such as maintaining the integrity of blood-brain barrier and regulating cerebral blood flow. Loss of pericytes can lead to pathological processes such as brain microcirculation dysfunction and blood-brain barrier destruction, and is associated with a variety of diseases, but there are few studies on the correlation between them and cerebral small vessel disease. This article mainly reviews the role of pericytes in the pathogenesis of cerebral small vessel disease.
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栏目名称
DOI
10.3760/cma.j.issn.1673-4165.2021.06.012
发布时间
2021-06-28（万方平台首次上网日期，不代表论文的发表时间）
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