摘要褪黑素主要是由松果体合成的一种激素,作为脊椎动物内分泌系统生物钟的同步器,其受体广泛分布于垂体、下丘脑、视网膜、肾脏和皮肤及其附属器,有着多种生理活性,按光周期信号调节生物体昼夜节律和季节节律.除了参与中枢、生殖及免疫系统的生理活动,研究表明,褪黑素与毛发生长也有密切关系,还可影响动物皮毛的季节性更替.目前已有用褪黑素制品治疗雄激素性秃发的实验性研究.

abstractsMelatonin is a hormone produced by pineal gland.As a synchronizer of endocrine svstem bioclock in vertebrate,melatonin possesses many physiological activities.e.g.regulating the biologic rhythm according to photoperiod,by its receptors widely distributed in pituitary gland,hypothalamus,optomeninx,kidneys,skin and its appendages,etc.In addition to central nervous system,genital system and immune system,melatonin is closely related to hair growth,and can affect the seasonal shift of animals' fur.So far.pilot trials have been conducted on the treatment of androgenetic alopecia with melatonin.