摘要白癜风是一种常见的色素脱失性疾病,临床上以表皮黑素细胞破坏缺失而出现色素脱失斑为主要特征.其发病机制不明.近年来发现,通过体内外各种因素,引起白癜风患者体内的氧化-抗氧化系统平衡失调,导致体内的活性氧簇或活性氮簇增加,引起氧化应激,造成黑素细胞损伤.随着研究的深入,一些人工或天然抗氧化剂应用于白癜风的临床治疗,如槲皮素、胎盘制剂、银杏叶提取液等.

abstractsVitiligo is an acquired depif;mentation disorder mainly characterized by depigmented patches induced by the destruction of epidermal melanocytes. Pathogenetic mechanisms of vitiligo remain unanswered. Recendy, it has been revealed that intemal and extemal factors can cause oxidant-antioxidant imbalance followed by accumulation of reactive oxygen species and reactive nitrogen species in vivo, which in tum leads to oxidative stress and melanocyte destruction. Recently. some artificial and natural antioxidants have been applied to clinical treatment of vitiligo, such as quercetin, placental preparations,ginkgo biloba extract, and so on.