摘要白癜风是一种与黑素细胞缺失有关的色素脱失性皮肤病,易诊难治,尤其对难治部位,诸如嘴唇、生殖器、头皮、眼睑、肘膝部及四肢、掌跖足底等疗效更差.就近年来对难治部位的有效疗法,如药物、外科移植术、光疗及联合疗法等进行概述.根据难治部位的临床特点,选用合理的治疗方案,以提高难治部位的疗效,指导临床治疗.

abstractsVitiligo is a depigmentary skin disorder characterized by a chronic and progressive loss of melanocytes(MC). It is easy to diagnose, but difficult to treat. Certain areas such as the lips, genitals, scalp,eyelids, elbows and knees, extremities, palms and soles are considered as difficuh-to-treat areas. This paper describes the latest progress in effective therapies of vitiligo on difficult-to-treat sites, including medicine,surgical transplant, phototherapy and combination treatments. To choose a reasonable treatment strategy based on the characteristic of lesional sites may improve the clinical efficacy of vitiligo treatment.