换一批
换一批摘要银屑病的发病机制与免疫关系密切,近几年研究倾向于银屑病是Th1/Th17混合途径的免疫性疾病.银屑病的发病中除了有树突细胞、T细胞、角质形成细胞以及Tb1型的细胞因子如白介素12、白介素18等参与外,还有Th17型细胞因子,如白介素23及白介素22等的参与,Th17型免疫反应可能在银屑病发病中起到重要的作用.
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abstractsThe pathogenesis of psoriasis is closely associated with immune system. Most of recent studies have suggested that psoriasis is a mixed Thl/Thl7 immunological disease. Besides dendritic cells, T cells, keratinocytes and Thl type cytokines such as interleukin (IL)-12 and IL-18, Thl7 type cytokines such as IL-23 and IL-22 also participate in the development of psoriasis. Thl7 type immune response may play an essential role in the pathogenesis of psoriasis.
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