摘要性病性淋巴肉芽肿是由L型沙眼衣原体引起的一种经典的性传播疾病.临床上以生殖器溃疡、腹股沟淋巴结病或生殖器肛门直肠综合征为主要特征,病程慢性.中国仅有散发病例报道.近年在欧美国家的男男同性性行为者中有性病性淋巴肉芽肿暴发流行,其流行菌株主要是L2b型沙眼衣原体.男男同性性行为者人群中的性病性淋巴肉芽肿多为有症状的直肠炎,有多性伴或高危性行为,常合并HIV感染、其他性传播疾病和血源性疾病.分子生物学检测技术在性病性淋巴肉芽肿的诊断与鉴定中发挥着重要的作用.

abstractsLymphogranuloma venereum ( LGV ) is a classical sexually transmitted disease (STD) caused by Chlamydia trachomatis serovar L (L1,L2 and L3).Clinically,LGV mainly manifests as chronic genital ulceration,inguinal lymphadenopathy or anogenitorectal syndrome.Cases of LGV have been sporadiclly reported in China.Recently outbreaks of LGV have been observed among men who have sex with men (MSM) in European countries and the United States,and the predominant LGV strain was Chlamydia trachomatis serovar L2b.LGV among MSM usually manifests as asymptomatic proctitis complicated by other STDs and blood-borne diseases including HIV infection,and is associated with having multiple sex partners or high risk behavior.Molecular techniques play an important role in the diagnosis and confirmation of LGV.