摘要掌跖脓疱病是一种病因不明,发生于掌跖部位的慢性、炎症性、复发性疾病,该病以在红斑的基础上周期性发生簇集性无菌性小脓疱,伴角化、脱屑为临床特征,好发年龄在30 ～ 50岁,女性比男性多见.近年来,随着掌跖脓疱病发病率的增加,带动了一系列关于其病因的研究和临床试验.分别就掌跖脓疱病与免疫、吸烟因素、金属致敏、血浆钙离子水平以及感染等诸方面的关系进行概述,旨在为掌跖脓疱病患者的诊疗带来一定的帮助.

abstractsPalmoplantar pustulosis is a chronic,recurrent and inflammatory skin disorder of unclear etiology.Clinically,it is characterized by periodic appearance of crops of small aseptic pustules that arise from an erythematous base and is complicated by keratinization and desquamation.It often occurs in women aged 30 to 50 years.Recently,with the increase in the incidence of palmoplantar pustulosis,a series of basic experiments and clinical trials have been carried out on its etiology.The authors summarize the relationship of palmoplantar pustulosis with immunity,smoking,sensitizing metals,plasma calcium,and infection.