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银屑病和代谢综合征是两种临床常见病,可合并出现.银屑病是慢性复发性炎症性多因素皮肤病,发病与遗传、免疫,感染、吸烟以及精神紧张等因素有关.代谢综合征以中心性肥胖为核心,合并高血糖、高血压和脂代谢紊乱等多种代谢异常集结的病理状态.银屑病与代谢综合征发病机制密切相关,且存在共同的细胞因子表达.对代谢综合征的研究可以为银屑病的治疗提供新的靶位.

Psoriasis and metabolic syndrome are two common clinical conditions,and often occur concurrently.Psoriasis is a chronic,relapsing,multifactorial inflammatory skin disease,whose pathogenesis is associated with genetic factors,immunological factors,infection,smoking,mental stress and other environmental factors.Metabolic syndrome is a pathological condition primarily presenting as central obesity accompanied by hyperglycemia,hypertension,lipid disorders and other metabolic abnormalities.The pathogenesis of psoriasis is closely related to that of metabolic syndrome,and some cytokines are simultaneously involved in their pathogenesis.To study metabolic syndrome may provide new targets for the treatment of psoriasis.