摘要疣状黄瘤是一种少见的疣状或菜花状生长的良性增生性疾病,好发于口腔,少数可发生于口腔以外的皮肤,皮损可单发或多发,生长缓慢,且患者常无自觉症状.组织病理为其重要的确诊依据,特点为真皮乳头大量泡沫细胞.其发病机制尚未明确,主要与刺激、创伤、炎症、淋巴水肿及遗传等相关,本病可单独发病,也可合并其他疾病,如盘状红斑狼疮、扁平苔藓、硬化萎缩性苔藓、动静脉血管瘤、淋巴水肿、移植物抗宿主反应、先天性偏侧发育不良伴鱼鳞病样红皮病及肢体缺陷综合征、营养不良性大疱性表皮松解症、毛细血管渗漏综合征等.

abstractsVerruciform xanthoma is an uncommon verruciform or cauliflower-like benign hyperplastic disease that occurs most frequently in the oral cavity and sometimes outside it.The lesions of verruciform xanthomacan be solitary or multiple,and grow slowly with no subjective symptoms.Histopathological manifestations are important evidence for final diagnosis,and are characterized by the presence of a large number of foam cells in the dermal papilla.The pathogenesis of verruciform xanthoma is still unclear,and is mainly associated with stimulation,trauma,inflammation,lymphedema,heredity,and so on.Verruciform xanthoma can occur alone or together with other diseases,such as discoid lupus erythematosus,lichen planus,lichen sclerosus et atrophicus,arteriovenous hemangioma,lymphedema,graft-versus-host disease,congenital hemidysplasia with ichthyosiform erythroderma and limb defects,dystrophic epidermolysis bullosa,capillary leak syndrome,etc.