摘要肿瘤是严重威胁人类生命和社会发展的重大疾病,已成为全球最重要的医疗卫生问题之一.随着疾病模式的转变和人口老龄化趋势,使得我国癌症患者的负担日益加重.手术是肿瘤治疗的重要手段之一.临床中大多选择各类麻醉镇痛方法完成外科手术、侵入性检查等操作,因此为肿瘤患者提供安全有效的麻醉镇痛药物是保障其顺利检查并接受治疗的关键因素.右美托咪啶(Dex)是一种新型α2-肾上腺素受体激动剂,相较于传统阿片类药物具有较为理想的有效性及安全性,给药后可获得镇静、抗焦虑及镇痛作用.对Dex在肿瘤患者中的应用进展进行综述旨在对临床治疗予以指导.

abstractsCancer is a serious disease threatening human life and social development,and has become one of the most important medical and health problems in the world.As the changing of disease patterns change and the trending of aging population,the burden of cancer patients is increasing in China.In clinical practice,various anesthesia methods are indispensable to complete surgery,invasive examinations and other operations.Therefore,safe and effective narcotic analgesic for cancer patients is the key factor for successful completion of examination and treatment.Dexmedetomidine (Dex) is a novel α2-adrenergic receptor agonist.Comparing with traditional opioids,Dex is more effective and safer,and can provide sedation,anxiolytic and analgesia after administration.In this paper,the progress of the usage of Dex in cancer patients was summarized to guide clinical treatment programs.