换一批摘要细胞迁移在肿瘤细胞转移中不可缺少,肌动蛋白的聚合、细胞的黏附、肌球蛋白的收缩会促进细胞的迁移过程.其中肌动蛋白聚合和收缩的协同调控机制以及活体中肌动蛋白的动力学作用在此过程中也较为重要,进而调控着肿瘤转移的发生、发展.
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abstractsCell motility and chemotaxis can make important contributions to metastatic cascade. Cell motility is needed in these processes, which is driven by cycles of actin polymerization, cell adhesion and actomyosin contraction. Coordinated regulation of actin and action of dynamics would regulate metastasis and metastatic progression, reducing dissemination of tumor cells, which is very important in this process.
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